ArticleScientific reports2023
Low maternal education increases the risk of Type 1 Diabetes, but not other autoimmune diseases: a mediating role of childhood BMI and exposure to serious life events.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Vitamin supplementation and its effect on incident type 1 diabetes mellitus and islet autoimmunity: a systematic review and meta-analysis.Frontiers in immunology · 2025Pooled it
- Geospatial clustering of type 1 diabetes in Sweden: a cohort study based on all residential locations from birth to diagnosis.Diabetologia · 2026Article
- Early Life Physical Activity May Reduce the Risk of Developing Type 1 Diabetes: The Longitudinal ABIS Study.Diabetes/metabolism research and reviews · 2025Article
- Stable heritability of type 1 diabetes in a Swedish Nationwide Cohort Study.Nature communications · 2025Article
- Article
- Infections and antibiotic use in early childhood have limited importance in developing manifest type 1 diabetes - The ABIS cohort study.Frontiers in endocrinology · 2025Article
- Early environmental predictors for attention-deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD) and their co-occurrence: The prospective ABIS-Study.Scientific reports · 2024Article
- The emergence of obesity in type 1 diabetes.International journal of obesity (2005) · 2024Review
- Exploring the relationship between exanthematous diseases and early-onset type 1 diabetes in children.Jornal de pediatriaArticle
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this paper was to investigate if socioeconomic status (SES), measured by maternal education and household income, influenced the risk of developing autoimmune disease (Type 1 Diabetes, Celiac disease, Juvenile Idiopathic Arthritis, Crohn's disease, Ulcerative colitis, and autoimmune thyroid disease), or age at diagnosis, and to analyse pathways between SES and autoimmune disease. We used data from the All Babies in Southeast Sweden (ABIS) study, a population-based prospective birth cohort, which included children born 1997-1999. Diagnoses of autoimmune disease was collected from the Swedish National Patient Register Dec 2020. In 16,365 individuals, low maternal education, but not household income, was associated with increased risk of Type 1 Diabetes; middle education RR 1.54, 95% CI 1.06, 2.23; P 0.02, low education RR 1.81, 95% CI 1.04, 3.18; P 0.04. Maternal education and household income was not associated with any other autoimmune disease and did not influence the age at diagnosis. Part of the increased risk of Type 1 Diabetes by lower maternal education was mediated by the indirect pathway of higher BMI and higher risk of Serious Life Events (SLE) at 5 years of age. The risk of developing Type 1 Diabetes associated to low maternal education might be reduced by decreasing BMI and SLE during childhood.
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