Evidence map›Paper›PMID 37061212›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2023

Immediate and contributory causes of death in patients hospitalized with COVID-19.

Adeel A Butt, Mylai D Guerrero, Elenor B Canlas, Husni Al-Dwairi, Aseel Hatem Subhi Alzibdeh, Thasneem Odaippurath, Ali Ahmed Sheikh Saleh Alkeldi, Mohammad Fawaz Saber Mohammad, Anil G Thomas, Sherin Shams and 8 more

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In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 2 countries.

Adeel A ButtCorporate Quality and Patient Safety Department, Hamad Medical Corporation, Doha, Qatar; Departments of Medicine and Population Health Sciences, Weill Cornell Medicine New York, New York, USA; Departments of Medicine and Population Health Sciences, Weill Cornell Medicine, Ar-Rayyan, Qatar. Electronic address: aabutt@hamad.qa.
Mylai D GuerreroCorporate Quality and Patient Safety Department, Hamad Medical Corporation, Doha, Qatar.
Elenor B CanlasCorporate Quality and Patient Safety Department, Hamad Medical Corporation, Doha, Qatar.
Husni Al-DwairiCorporate Quality and Patient Safety Department, Hamad Medical Corporation, Doha, Qatar.
Aseel Hatem Subhi AlzibdehCommunicable Diseases Center, Hamad Medical Corporation, Doha, Qatar.
Thasneem OdaippurathCommunicable Diseases Center, Hamad Medical Corporation, Doha, Qatar.
Ali Ahmed Sheikh Saleh AlkeldiCorporate Quality and Patient Safety Department, Hamad Medical Corporation, Doha, Qatar.
Mohammad Fawaz Saber MohammadCorporate Quality and Patient Safety Department, Hamad Medical Corporation, Doha, Qatar.
Anil G ThomasCorporate Quality and Patient Safety Department, Hamad Medical Corporation, Doha, Qatar.
Sherin ShamsCorporate Quality and Patient Safety Department, Hamad Medical Corporation, Doha, Qatar.
Samah SaleemCorporate Quality and Patient Safety Department, Hamad Medical Corporation, Doha, Qatar.
Fathima HananaCorporate Quality and Patient Safety Department, Hamad Medical Corporation, Doha, Qatar.
Anvar Hassan KaleeckalBusiness Intelligence Unit, Hamad Medical Corporation, Doha, Qatar.
Ali Nizar LatifBusiness Intelligence Unit, Hamad Medical Corporation, Doha, Qatar.
Riyazuddin Mohammad ShaikBusiness Intelligence Unit, Hamad Medical Corporation, Doha, Qatar.
Abdullatif Al-KhalCommunicable Diseases Center, Hamad Medical Corporation, Doha, Qatar.
Muna Al-MaslamaniCommunicable Diseases Center, Hamad Medical Corporation, Doha, Qatar.
Abdul-Badi Abou-SamraCorporate Quality and Patient Safety Department, Hamad Medical Corporation, Doha, Qatar.
Hamad Medical Corporation · QACornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAccurate determination of the immediate causes of death in patients with COVID-19 is important for optimal care and mitigation strategies.

methodsAll deaths in Qatar between March 01, 2020, and August 31, 2022, flagged for likely relationship to COVID-19 were reviewed by two independent, trained reviewers using a standardized methodology to determine the immediate and contributory causes of death.

resultsAmong 749 flagged deaths, the most common admitting diagnoses were respiratory tract infection (91%) and major adverse cardiac event (MACE, 2.3%). The most common immediate causes of death were COVID-19 pneumonia (66.2%), MACE (7.1%), hospital-associated pneumonia (HAP, 6.8%), bacteremia (6.3%), disseminated fungal infection (DFI, 5.2%), and thromboembolism (4.5%). After COVID-19 pneumonia, MACE was the predominant cause of death in the first 2 weeks but declined thereafter. No death occurred due to bacteremia, HAP, or DFI in the first week after hospitalization, but became increasingly common with increased length of stay in the hospital accounting for 9%, 12%, and 10% of all deaths after 4 weeks in the hospital, respectively.

conclusionNearly one-third of patients with COVID-19 infection die of non-COVID-19 causes, some of which are preventable. Mitigation strategies should be instituted to reduce the risk of such deaths.

Indexed as

COVID-19Cause of DeathHospitalizationHospitalsHumansSARS-CoV-2Cause of deathCOVID-19MortalitySARS-CoV-2

Identifiers

PMID37061212
PMCPMC10102704
OpenAlexW4365517908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.