Evidence map›Paper›PMID 37061143›Full record

ReviewAlcohol (Fayetteville, N.Y.)2023

Alcohol and Immunology: Mechanisms of multi-organ damage. Summary of the 2022 alcohol and Immunology research interest group (AIRIG) meeting.

Rachel H McMahan, Paige Anton, Leon G Coleman, Gail A M Cresci, Fulton T Crews, Kathryn M Crotty, Marisa E Luck, Patricia E Molina, Vidula Vachharajani, Joanne Weinberg and 4 more

Open access · greenAbstract readReview
In one paragraph

Review in Alcohol (Fayetteville, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 2 countries.

Rachel H McMahanDivision of GI, Trauma, and Endocrine Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Alcohol Research Program, University of Colorado Anschutz Medical Campus, Aurora, CO, United States. Electronic address: Rachel.Mcmahan@cuanschutz.edu.
Paige AntonAlcohol Research Program, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Leon G ColemanDepartment of Pharmacology, Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States.
Gail A M CresciDepartments of Pediatric Gastroenterology, Hepatology & Nutrition, Cleveland Clinic Children's Hospital and Inflammation & Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States.
Fulton T CrewsDepartment of Pharmacology, Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States.
Kathryn M CrottyDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University, Atlanta, GA, United States; Atlanta Veterans Affairs Health Care System, Decatur, GA, United States.
Marisa E LuckAlcohol Research Program, Burn & Shock Trauma Research Institute, Department of Surgery, Integrative Cell Biology Program, Stritch School of Medicine, Loyola University Chicago Health Sciences Division, Maywood, IL, United States.
Patricia E MolinaDepartment of Physiology and Comprehensive Alcohol Research Center, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Vidula VachharajaniDepartment of Inflammation and Immunity, Critical Care Medicine, Respiratory Institute, Lerner Research Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, United States.
Joanne WeinbergDepartment of Cellular & Physiological Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Samantha M YeligarDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University, Atlanta, GA, United States; Atlanta Veterans Affairs Health Care System, Decatur, GA, United States.
Mashkoor A ChoudhryAlcohol Research Program, Burn & Shock Trauma Research Institute, Department of Surgery, Integrative Cell Biology Program, Stritch School of Medicine, Loyola University Chicago Health Sciences Division, Maywood, IL, United States.
Rebecca L McCulloughAlcohol Research Program, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Elizabeth J KovacsDivision of GI, Trauma, and Endocrine Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Alcohol Research Program, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Molecular Biology Graduate Program, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States; Rocky Mountain Regional Veterans Affairs Medical Center, Aurora, CO, United States.
University of Colorado Anschutz Medical Campus · USEmory University · USLoyola University Chicago · USUniversity of North Carolina at Chapel Hill · USCleveland Clinic · USCleveland Clinic Lerner College of Medicine · USLouisiana State University Health Sciences Center New Orleans · USUniversity of British Columbia · CA

Funding

Translational Research/Education ComponentP60AA009803 · NIAAA · LSU HEALTH SCIENCES CENTER · PI DAVID A WELSH · 2004 to 2026
$42.6M
BIOMEDICAL ALCOHOL RESEARCH TRAINING PROGRAMT32AA007577 · NIAAA · LSU HEALTH SCIENCES CENTER · PI PATRICIA E. MOLINA · 1999 to 2026
$9.6M
Aging, macrophage mediators, and burn trauma: SupplementR01AG018859 · NIA · UNIVERSITY OF COLORADO DENVER · PI KOVACS, ELIZABETH J. · 2001 to 2024
$7.6M
UNC-CH NADIA Underage Drinking and Adult Brain Morphology in RatsU01AA020023 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CREWS, FULTON T · 2010 to 2024
$7.5M
PILOT--IMPACT OF ALCOHOLISM ON AIDS ASOCIATED MUSCLE WASTINGP50AA009803 · NIAAA · LOUISIANA STATE UNIV HSC NEW ORLEANS · PI NELSON, STEVE · 1994 to 2003
$7.2M
UNC-CH NADIA Administrative CoreU24AA020024 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CREWS, FULTON T · 2010 to 2024
$6.6M
Graduate Training in the Pharmacological StudiesT32GM008602 · NIGMS · EMORY UNIVERSITY · PI HALL, RANDY A. · 1996 to 2021
$5.1M
Training in Neuroimmunoendocrine Effects of AlcoholT32AA013527 · NIAAA · LOYOLA UNIVERSITY CHICAGO · PI CHOUDHRY, MASHKOOR A · 2002 to 2021
$4.4M
Fetal Alcohol Spectrum Disorders in Adults: Health and NeurobehaviorU01AA026108 · NIAAA · EMORY UNIVERSITY · PI Tamara Sonia Bodnar, Claire D. Coles · 2017 to 2026
$3.9M
Alcohol Intoxication and Postburn Intestinal ImmunityR01AA015731 · NIAAA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHOUDHRY, MASHKOOR A · 2007 to 2017
$3.8M
Alcohol and Burn Trauma: Multi-organ Inflammatory ResponsesR35GM131831 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI ELIZABETH J. KOVACS · 2019 to 2026
$3.5M
Bioenergetic and Epigenetic Reprogramming by Obesity in SepsisR01GM099807 · NIGMS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI VACHHARAJANI, VIDULA · 2012 to 2020
$3.1M
BLRD VA I01 BX004335NIAAA NIH HHS F31 AA029938NIAAA NIH HHS F31 AA030213NIAAA NIH HHS K08 AA024829NIAAA NIH HHS P50 AA009803NIAAA NIH HHS P60 AA009803NIAAA NIH HHS R00 AA025386NIAAA NIH HHS R01 AA015731NIAAA NIH HHS R01 AA022460NIAAA NIH HHS R01 AA026086NIAAA NIH HHS R01 AA028043NIAAA NIH HHS R01 AA028763NIAAA NIH HHS R01 AA028924NIAAA NIH HHS R13 AA020768NIAAA NIH HHS R21 AA026295NIAAA NIH HHS R21 AA028599NIAAA NIH HHS T32 AA007577NIAAA NIH HHS T32 AA013527NIAAA NIH HHS U01 AA020023NIAAA NIH HHS U01 AA026101NIAAA NIH HHS U01 AA026108NIAAA NIH HHS U24 AA020024NIAAA NIH HHS U54 AA030463NIA NIH HHS R01 AG018859NIDDK NIH HHS F30 DK123929NIEHS NIH HHS T32 ES029074NIGMS NIH HHS R01 GM099807NIGMS NIH HHS R01 GM128242NIGMS NIH HHS R35 GM131831NIGMS NIH HHS T32 GM008602
6 · The paper itself

Abstract

On October 26th, 2022 the annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held as a satellite symposium at the annual meeting of the Society for Leukocyte Biology in Hawaii. The 2022 meeting focused broadly on the immunological consequences of acute, chronic, and prenatal alcohol exposure and how these contribute to damage in multiple organs and tissues. These included alcohol-induced neuroinflammation, impaired lung immunity, intestinal dysfunction, and decreased anti-microbial and anti-viral responses. In addition, research presented covered multiple pathways behind alcohol-induced cellular dysfunction, including mitochondrial metabolism, cellular bioenergetics, gene regulation, and epigenetics. Finally, the work presented highlighted potential biomarkers and novel avenues of treatment for alcohol-induced organ damage.

Indexed as

Prenatal Exposure Delayed EffectsPublic OpinionEthanolFemaleHawaiiHumansInflammationPregnancyEthanoladvanced agebrainepigeneticsethanolfetal programminginflammationintestinelungmacrophagemetabolismmitochondrianeurogenesisT cell

Identifiers

PMID37061143
PMCPMC10330898
OpenAlexW4365458338

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.