Evidence map›Paper›PMID 37060394›Full record

ArticleEJNMMI research2023

Multiparametric dynamic whole-body PSMA PET/CT using [

André H Dias, Mads R Jochumsen, Helle D Zacho, Ole L Munk, Lars C Gormsen

Open access · goldAbstract read
In one paragraph

Article in EJNMMI research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Comparison ofProstate cancer and prostatic diseases · 2024
    Pooled it
  2. Quantitative [Molecular imaging and biology · 2026
    Trial
  3. Mitigating bladder signal inEJNMMI physics · 2026
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  6. Quantitative characterization ofMolecular imaging and radionuclide therapy · 2026
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  12. End-to-end [Abdominal radiology (New York) · 2025
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  13. Synthesis, preclinical assessment, and first-in-human study of [European journal of nuclear medicine and molecular imaging · 2025
    Article
  14. Parametric net influx rate imaging ofAnnals of nuclear medicine · 2024
    Article
  15. Combined whole-body dynamic and static PET/CT with low-dose [European journal of nuclear medicine and molecular imaging · 2024
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  16. Dynamic whole-body [EJNMMI research · 2024
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  17. Assessing dynamic metabolic heterogeneity in prostate cancer patients via total-body [European journal of nuclear medicine and molecular imaging · 2024
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  18. Comparison of parametric imaging and SUV imaging with [European journal of nuclear medicine and molecular imaging · 2024
    Article
  19. Review
  20. Direct Patlak Reconstruction of [International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

André H DiasDepartment of Nuclear Medicine & PET Centre, Aarhus University Hospital, Palle Juul-Jensens Boulevard 165, 8200, Aarhus N, Denmark. andre.dias@auh.rm.dk.ORCID http://orcid.org/0000-0003-3184-3468
Mads R JochumsenDepartment of Nuclear Medicine & PET Centre, Aarhus University Hospital, Palle Juul-Jensens Boulevard 165, 8200, Aarhus N, Denmark.ORCID http://orcid.org/0000-0002-7676-2322
Helle D ZachoDepartment of Nuclear Medicine and Clinical Cancer Research Centre, Aalborg University Hospital, Aalborg, Denmark.ORCID http://orcid.org/0000-0001-9089-288X
Ole L Munk *Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Palle Juul-Jensens Boulevard 165, 8200, Aarhus N, Denmark.ORCID http://orcid.org/0000-0002-7232-5088
Lars C Gormsen *Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Palle Juul-Jensens Boulevard 165, 8200, Aarhus N, Denmark.ORCID http://orcid.org/0000-0002-0144-1305
Aarhus University · DKAalborg University Hospital · DKAarhus University Hospital · DK

Funding

Novo Nordisk Fonden NNF19OC0055100
6 · The paper itself

Abstract

backgroundRoutine prostate-specific membrane antigen (PSMA) positron emission tomography (PET) performed for primary staging or restaging of prostate cancer patients is usually done as a single static image acquisition 60 min after tracer administration. In this study, we employ dynamic whole-body (D-WB) PET imaging to compare the pharmacokinetics of [

methodsTwenty male patients with prostate cancer were examined using a D-WB PSMA PET protocol. Ten patients were scanned with [

resultsThe two PSMA tracers exhibited markedly different pharmacokinetics in organs: reversible for [

conclusionD-WB PET/CT is feasible for both PSMA tracers allowing for direct reconstruction of parametric Ki images. The use of multiparametric PSMA images increased TBR but did not lead to the detection of more lesions. For quantitative whole-body Ki imaging, [

Indexed as

Dynamic whole-body PETOncologyParametric imagingPatlakProstate cancerPSMA

Identifiers

PMID37060394
PMCPMC10105814
OpenAlexW4365810970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.