Evidence map›Paper›PMID 37060199›Full record

ArticleInternational wound journal2023

Spatial and temporal changes in biophysical skin parameters over a category I pressure ulcer.

Nkemjika S Abiakam, Hemalatha Jayabal, Davide Filingeri, Dan L Bader, Peter R Worsley

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in International wound journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06420102 completednot on this map

Detecting Changes in Skin Status Over the Site of a Stage 1 Pressure Ulcer Using Biophysical Sensors and Biomarkers

TypeobservationalSponsorUniversity of SouthamptonRan2021 to 2023Enrolled50ConditionsPressure UlcerArmsBiophysical and biochemical skin assessment
NCT07560683 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Investigation of Skin Barrier Function Using Biosensor Methods in Risky Skin Regions and Developed Pressure Injuries in Intensive Care Patients, and Identification of Influencing Factors: The SKIN-BAR Project

TypeobservationalSponsorKoç UniversityRan2026 to 2028Enrolled156ConditionsPressure Injuries, Skin Failure, Skin Abnormalities, Biophysical Parameters of Skin
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nkemjika S AbiakamFaculty of Environmental and Life Sciences, School of Health Sciences, University of Southampton, Southampton, UK.ORCID https://orcid.org/0000-0002-9599-7274
Hemalatha JayabalFaculty of Environmental and Life Sciences, School of Health Sciences, University of Southampton, Southampton, UK.
Davide FilingeriFaculty of Environmental and Life Sciences, School of Health Sciences, University of Southampton, Southampton, UK.
Dan L BaderFaculty of Environmental and Life Sciences, School of Health Sciences, University of Southampton, Southampton, UK.
Peter R WorsleyFaculty of Environmental and Life Sciences, School of Health Sciences, University of Southampton, Southampton, UK.
University of Southampton · GB

Funding

European Union's Horizon 2020H2020 Marie Skłodowska-Curie Actions 811965
6 · The paper itself

Abstract

In acute care facilities, the detection of pressure ulcers (PUs) relies on visual and manual examination of the patient's skin, which has been reported to be inconsistent and may lead to misdiagnosis. In skin and wound research, various biophysical parameters have been extensively employed to monitor changes in skin health. Nonetheless, the transition of these measures into care settings as part of a routine clinical assessment has been limited. This study was designed to examine the spatial and temporal changes in skin biophysical parameters over the site of a category I PU, in a cohort of hospitalised patients. Thirty patients, each presenting with a category I PU, were enrolled in the study. Skin integrity was assessed at the PU-compromised site and two adjacent areas (5 and 10 cm away). Data was collected over three sessions to examine both temporal differences and longitudinal changes. Skin integrity was assessed using two biophysical parameters, namely, transepidermal water loss (TEWL) and stratum corneum (SC) hydration. In addition, the influence of intrinsic factors, namely, incontinence and mobility status, on the parameters was evaluated. TEWL values at the sites compromised by PU were statistically significantly greater (P < .001) than corresponding values at the adjacent control sites at 5 and 10 cm, which were consistent with a normative range (<20 g/h/m

Indexed as

Pressure UlcerEpidermisFemaleHumansSkinSuppurationWaterWateracute care settingbiophysical parameterspressure ulcer (PU)skin assessmentskin health

Identifiers

PMID37060199
PMCPMC10502241
OpenAlexW4365811177

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.