Evidence map›Paper›PMID 37059973›Full record

ArticleBMC public health2023

The association between combustible/electronic cigarette use and stroke based on national health and nutrition examination survey.

Jing Shi, Lijun Xiong, Jun Guo, Yan Yang

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. E-cigarette Use and Incident Cardiometabolic Conditions in the All of Us Research Program.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Young users of electronic cigarettes exhibit reduced cardiorespiratory fitness.Journal of applied physiology (Bethesda, Md. : 1985) · 2024
    Article
  12. Assessing the Consequences of Smoking Tobacco Products with Consideration of the Forced Oscillation Technique.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jing Shi *Health Management Center, Tongji Medical College, The Central Hospital of Wuhan, Huazhong University of Science and Technology, 430014, Wuhan, China.
Lijun Xiong *Health Management Center, Tongji Medical College, The Central Hospital of Wuhan, Huazhong University of Science and Technology, 430014, Wuhan, China.
Jun Guo *Health Management Center, Tongji Medical College, The Central Hospital of Wuhan, Huazhong University of Science and Technology, 430014, Wuhan, China.
Yan YangDepartment of Neurology, Tongji Medical College, The Central Hospital of Wuhan, Huazhong University of Science and Technology, 430014, Wuhan, China. yangyan13333@163.com.
Huazhong University of Science and Technology · CNCentral Hospital of Wuhan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study aims to analyze the association between combustible/electronic cigarettes and the risk of stroke.

methodsWe obtained data from the 2017-2018 National Health and Nutrition Examination Survey (NHANES). The stroke history and combustible/electronic cigarette use were acquired by questionnaires. Considering the sole or dual use of combustible cigarettes and electronic cigarettes (e-cigarettes), we divided all the individuals into four subgroups, including nonsmokers (reference group), sole combustible cigarette, sole e-cigarette, and dual use of both combustible cigarettes and e-cigarettes. We performed multivariable logistic regression to determine the association between cigarette use with the prevalence of stroke. We used odds ratios (ORs) with 95% confidence intervals (CIs) to show the effect size. Finally, we developed a prediction model to evaluate the risk of stroke for individuals with combustible or electronic cigarette use based on a random forest model.

resultsWe included a total of 4022 participants in the study. The median age was 55, and 48.3% of the participants were males. When we adjusted for age, gender, education attainment, race, total-to-HDL cholesterol (< 5.9 or ≥ 5.9), diabetes, hypertension, and alcohol consumption, the groups of sole e-cigarette use, sole combustible cigarette use, and dual use of combustible and electronic cigarettes were significantly associated with the prevalence of stroke with ORs (with 95%CI) of 2.07 (1.04-3.81), 2.36 (1.52-3.59), 2.34 (1.44-3.68), respectively. In the testing set, the AUC was 0.74 (95%CI = 0.65-0.84), sensitivity was 0.68, and specificity was 0.75.

conclusionSole e-cigarettes and dual use of e-cigarettes with combustible cigarettes might increase the risk of stroke.

Indexed as

Electronic Nicotine Delivery SystemsStrokeTobacco ProductsVapingFemaleHumansMaleNutrition SurveysClinical prediction model.Combustible cigaretteElectronic cigaretteSmokingStroke

Identifiers

PMID37059973
PMCPMC10103410
OpenAlexW4365514054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.