Evidence map›Paper›PMID 37059920›Full record

ReviewBiological trace element research2024

Nutraceutical and Health-Promoting Potential of Lactoferrin, an Iron-Binding Protein in Human and Animal: Current Knowledge.

Muhammad Faizan Ashraf, Dawood Zubair, Muhammad Noaman Bashir, Mahmoud Alagawany, Shabbir Ahmed, Qurban Ali Shah, Jameel Ahmed Buzdar, Muhammad Asif Arain

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biological trace element research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

  1. Pooled it
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  17. Special Issue "New Insights into Lactoferrin".International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Muhammad Faizan AshrafFatima Memorial Hospital, College of Medicine and Dentistry, Shadman, Lahore, Pakistan.
Dawood ZubairIqraa Medical Complex, Johar Town Lahore, Punjab, Pakistan.
Muhammad Noaman BashirTehsil Headquarter Hospital Burewala, Punjab, Pakistan.
Mahmoud AlagawanyPoultry Department, Agriculture Faculty, Zagazig University, Zagazig, 44519, Egypt. dr.mahmoud.alagwany@gmail.com.
Shabbir AhmedFaculty of Animal Husbandry & Veterinary Science, Sindh Agriculture University Tandojam, Tandojam, Pakistan.
Qurban Ali ShahFaculty of Veterinary and Animal Sciences, Lasbela University of Agriculture, Water and Marine Sciences, Uthal, 3800, Balochistan, Pakistan.
Jameel Ahmed BuzdarFaculty of Veterinary and Animal Sciences, Lasbela University of Agriculture, Water and Marine Sciences, Uthal, 3800, Balochistan, Pakistan.
Muhammad Asif ArainFaculty of Veterinary and Animal Sciences, Lasbela University of Agriculture, Water and Marine Sciences, Uthal, 3800, Balochistan, Pakistan. asifarain77@yahoo.com.
Lasbela University of Agriculture Water and Marine Science · PKIqra University · PKMayo Hospital · PKSindh Agriculture University · PKZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactoferrin is a natural cationic iron-binding glycoprotein of the transferrin family found in bovine milk and other exocrine secretions, including lacrimal fluid, saliva, and bile. Lactoferrin has been investigated for its numerous powerful influences, including anticancer, anti-inflammatory, anti-oxidant, anti-osteoporotic, antifungal, antibacterial, antiviral, immunomodulatory, hepatoprotective, and other beneficial health effects. Lactoferrin demonstrated several nutraceutical and pharmaceutical potentials and have a significant impact on improving the health of humans and animals. Lactoferrin plays a critical role in keeping the normal physiological homeostasis associated with the development of pathological disorders. The current review highlights the medicinal value, nutraceutical role, therapeutic application, and outstanding favorable health sides of lactoferrin, which would benefit from more exploration of this glycoprotein for the design of effective medicines, drugs, and pharmaceuticals for safeguarding different health issues in animals and humans.

Indexed as

Iron-Binding ProteinsLactoferrinAnimalsAntioxidantsDietary SupplementsGlycoproteinsHumansTransferrinAntioxidantsGlycoproteinsIron-Binding ProteinsLactoferrinTransferrinAnticancerAnti-inflammatoryAnti-microbialImmune responseLactoferrinNutraceuticals

Identifiers

PMID37059920
PMCPMC10104436
OpenAlexW4365503735

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.