Evidence map›Paper›PMID 37059897›Full record

Observational studyArchives of microbiology2023

Gut microbiota-mediated associations of green tea and catechin intakes with glucose metabolism in individuals without type 2 diabetes mellitus: a four-season observational study with mediation analysis.

Aoi Ito, Yuji Matsui, Masao Takeshita, Mitsuhiro Katashima, Chiho Goto, Kiyonori Kuriki

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Archives of microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Aoi ItoLaboratory of Public Health, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Suruga-Ku, Shizuoka, Japan.ORCID https://orcid.org/0000-0003-1008-3367
Yuji MatsuiR&D - Health & Wellness Products Research, Kao Corporation, Tokyo, Japan.
Masao TakeshitaR&D - Health & Wellness Products Research, Kao Corporation, Tokyo, Japan.
Mitsuhiro KatashimaR&D - Health & Wellness Products Research, Kao Corporation, Tokyo, Japan.
Chiho GotoDepartment of Health and Nutrition, Nagoya Bunri University, Aichi, Japan.
Kiyonori KurikiLaboratory of Public Health, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Suruga-Ku, Shizuoka, Japan. kuriki@u-shizuoka-ken.ac.jp.
Kao Corporation (Japan) · JPUniversity of Shizuoka · JPNagoya Bunri University · JP

Funding

Danone Institute of Japan Foundation, Japan 13-613Kao Research Council for the Study of Healthcare Science, Japan 14-332
6 · The paper itself

Abstract

This four-season observational study aimed to examine the mediating role of the gut microbiota in the associations between green tea and catechin intakes and glucose metabolism in individuals without type 2 diabetes mellitus (T2DM). In each of the 4 seasons, 85 individuals without T2DM (56 male [65.9%]; mean [standard deviation] age: 43.3 [9.4] years) provided blood samples, stool samples, 3-day weighed dietary records, and green tea samples. Catechin intake was estimated by analyzing the tea samples. Linear mixed-effects model analysis showed that green tea intake was negatively associated with fasting blood glucose and insulin levels, even after considering the seasonal variations. Of the gut microbial species associated with green tea intake, the mediation analysis revealed that Phocaeicola vulgatus mediated the association between green tea intake and fasting blood glucose levels. These findings indicate that green tea can improve glucose metabolism by decreasing the abundance of P. vulgatus that is associated with elevated blood glucose levels in individuals without T2DM.

Indexed as

CatechinDiabetes Mellitus, Type 2Gastrointestinal MicrobiomeAdultBlood GlucoseHumansMaleMediation AnalysisSeasonsTeaBlood GlucoseCatechinTeaCatechinGreen teaGut microbiotaMediation analysisSeasonType 2 diabetes mellitus

Identifiers

PMID37059897
PMCPMC10104920
OpenAlexW4365504283

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.