Evidence map›Paper›PMID 37059805›Full record

ArticleCommunications chemistry2023

Temporal nanofluid environments induce prebiotic condensation in water.

Andrea Greiner de Herrera, Thomas Markert, Frank Trixler

Abstract read
In one paragraph

Article in Communications chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The "Water Problem"(Life (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrea Greiner de HerreraDepartment of Earth and Environmental Sciences, Ludwig-Maximilians-Universität München, Theresienstraße 41, 80333, Munich, Germany.
Thomas MarkertInstitute of Theoretical Chemistry, Ulm University, Albert-Einstein-Allee 11, 89081, Ulm, Germany.ORCID http://orcid.org/0000-0002-2150-9442
Frank TrixlerDepartment of Earth and Environmental Sciences, Ludwig-Maximilians-Universität München, Theresienstraße 41, 80333, Munich, Germany. trixler@lrz.uni-muenchen.de.ORCID http://orcid.org/0000-0002-3090-4655

Funding

Bayerisches Staatsministerium für Umwelt und Verbraucherschutz (Bayerisches Staatsministerium für Umwelt Gesundheit und Verbraucherschutz) 71k-U8793-2015/14-9
6 · The paper itself

Abstract

Water is a problem in understanding chemical evolution towards life's origins on Earth. Although all known life is being based on water key prebiotic reactions are inhibited by it. The prebiotic plausibility of current strategies to circumvent this paradox is questionable regarding the principle that evolution builds on existing pathways. Here, we report a straightforward way to overcome the water paradox in line with evolutionary conservatism. By utilising a molecular deposition method as a physicochemical probe, we uncovered a synergy between biomolecule assembly and temporal nanofluid conditions that emerge within transient nanoconfinements of water between suspended particles. Results from fluorometry, quantitative PCR, melting curve analysis, gel electrophoresis and computational modelling reveal that such conditions induce nonenzymatic polymerisation of nucleotides and promote basic cooperation between nucleotides and amino acids for RNA formation. Aqueous particle suspensions are a geochemical ubiquitous and thus prebiotic highly plausible setting. Harnessing nanofluid conditions in this setting for prebiotic syntheses is consistent with evolutionary conservatism, as living cells also work with temporal nanoconfined water for biosynthesis. Our findings add key insights required to understand the transition from geochemistry to biochemistry and open up systematic pathways to water-based green chemistry approaches in materials science and nanotechnology.

Identifiers

PMID37059805
PMCPMC10104841

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.