Evidence map›Paper›PMID 37059065›Full record

ReviewCell2023

Metastasis.

Stefanie Gerstberger, Qingwen Jiang, Karuna Ganesh

Abstract readReview
In one paragraph

Review in Cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 566 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
566citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

566 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. The Anti-Metastatic Role of Aspirin in Cancer: A Systematic Review.International journal of molecular sciences · 2026
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Biomimetic Scaffold-Based 3D Models for Decoding Cancer Biology and Advancing Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  17. The Emerging Role of Ferroptosis in Pediatric Cancer Biology and Therapy.International journal of molecular sciences · 2026
    Review
  18. Article
  19. Review
  20. Article

506 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stefanie GerstbergerDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Qingwen JiangMolecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Karuna GaneshDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: ganeshk@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
The Center for Tumor-Immune Systems Biology at MSKCCU54CA274492 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Christina S Leslie, Alexander Y Rudensky · 2022 to 2026
$16.3M
Transition to Metastatic State: Lung Cancer, Pancreatic Cancer and Brain MetastasisU2CCA233284 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI PE'ER, DANA · 2018 to 2022
$12.9M
Mechanisms of Dynamic Transcriptional Reprogramming in Metastasis Stem CellsR37CA266185 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Karuna Ganesh · 2022 to 2026
$2.6M
Investigating L1CAM-dependent stem cell regeneration in metastasisK08CA230213 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI GANESH, KARUNA · 2018 to 2022
$1.3M
NCI NIH HHS K08 CA230213NCI NIH HHS P30 CA008748NCI NIH HHS R37 CA266185NCI NIH HHS U2C CA233284NCI NIH HHS U54 CA274492
6 · The paper itself

Abstract

Most cancer-associated deaths occur due to metastasis, yet our understanding of metastasis as an evolving, heterogeneous, systemic disease and of how to effectively treat it is still emerging. Metastasis requires the acquisition of a succession of traits to disseminate, variably enter and exit dormancy, and colonize distant organs. The success of these events is driven by clonal selection, the potential of metastatic cells to dynamically transition into distinct states, and their ability to co-opt the immune environment. Here, we review the main principles of metastasis and highlight emerging opportunities to develop more effective therapies for metastatic cancer.

Indexed as

NeoplasmsHumansNeoplasm Metastasis

Identifiers

PMID37059065
PMCPMC10511214

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.