Evidence map›Paper›PMID 37058914›Full record

ReviewCurrent opinion in microbiology2023

Bacterial lipid biophysics and membrane organization.

Lorna My Mitchison-Field, Brittany J Belin

Open access · hybridAbstract readReview
In one paragraph

Review in Current opinion in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Mimicking Cellular Membranes With Micropatterned Lipid Bilayers.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The Evolution of Lipids from Solvents to Substrates.Annual review of biophysics · 2026
    Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. A Minimalist Model Lipid System Mimicking the Biophysical Properties ofLangmuir : the ACS journal of surfaces and colloids · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lorna My Mitchison-FieldDepartment of Embryology, Carnegie Institution for Science, Baltimore, MD, USA; Department of Biology, Johns Hopkins University, Baltimore, MD, USA.
Brittany J BelinDepartment of Embryology, Carnegie Institution for Science, Baltimore, MD, USA; Department of Biology, Johns Hopkins University, Baltimore, MD, USA. Electronic address: belin@carnegiescience.edu.
Johns Hopkins University · US

Funding

CELLULAR AND MOLECULAR BIOLOGYT32GM007231 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 1985 to 2020
$18.4M
Cellular and Molecular BiologyT32GM141804 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI John Kim · 2021 to 2026
$5.1M
Lipid functions in bacterial cell organizationR35GM147015 · NIGMS · UNIVERSITY OF KENTUCKY · PI Brittany Jo Belin · 2022 to 2026
$1.8M
Role of hopanoid microbial lipids in a legume:microbe nitrogen-fixing symbiosisR00GM126141 · NIGMS · CARNEGIE INSTITUTION OF WASHINGTON, D.C. · PI BELIN, BRITTANY JO · 2020 to 2022
$747k
NIGMS NIH HHS R00 GM126141NIGMS NIH HHS R35 GM147015NIGMS NIH HHS T32 GM007231NIGMS NIH HHS T32 GM141804
6 · The paper itself

Abstract

The formation of lateral microdomains is emerging as a central organizing principle in bacterial membranes. These microdomains are targets of antibiotic development and have the potential to enhance natural product synthesis, but the rules governing their assembly are unclear. Previous studies have suggested that microdomain formation is promoted by lipid phase separation, particularly by cardiolipin (CL) and isoprenoid lipids, and there is strong evidence that CL biosynthesis is required for recruitment of membrane proteins to cell poles and division sites. New work demonstrates that additional bacterial lipids may mediate membrane protein localization and function, opening the field for mechanistic evaluation of lipid-driven membrane organization in vivo.

Indexed as

BacteriaMembrane ProteinsBiophysicsCardiolipinsCell MembraneMembranesCardiolipinsMembrane Proteins

Identifiers

PMID37058914
PMCPMC10523990
OpenAlexW4365458643

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.