Evidence map›Paper›PMID 37058685›Full record

ArticleJCO oncology practice2023

Fertility Preservation Decisional Turning Points for Adolescents and Young Adults With Cancer: Exploring Alignment and Divergence by Race and Ethnicity.

Mollie R Canzona, Karly Murphy, David Victorson, Onengiya Harry, Marla L Clayman, Thomas W McLean, Shannon L Golden, Bonnie Patel, Carla Strom, Denisha Little-Greene and 2 more

Abstract read
In one paragraph

Article in JCO oncology practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Early-Onset Colorectal Cancer: From Genetic Discovery to Clinical Innovation.American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · 2025
    Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mollie R CanzonaDepartment of Communication, Wake Forest University, Winston-Salem, NC.ORCID 0000-0001-9351-5422
Karly MurphyDepartment of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC.ORCID 0000-0001-9174-1338
David VictorsonMedical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL.
Onengiya HarryPediatrics-Rheumatology, Wake Forest Baptist Health, Winston-Salem, NC.
Marla L ClaymanDepartment of Population and Quantitative Research, UMass Chan School of Medicine, Worcester, MA.ORCID 0000-0001-8491-3672
Thomas W McLeanPediatrics-Hematology/and Oncology, Wake Forest Baptist Health, Winston-Salem, NC.
Shannon L GoldenGoldsmith Research Group, Winston-Salem, NC.ORCID 0000-0001-8214-6465
Bonnie PatelObstetrics and Gynecology, Reproductive Medicine, Wake Forest Baptist Health, Winston-Salem, NC.
Carla StromOperations, Office of Cancer Health Equity, Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, NC.
Denisha Little-GreeneWake Forest School of Medicine, Winston-Salem, NC.
Siba SakerDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, MA.ORCID 0000-0002-8441-1979
John M SalsmanDepartment of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC.ORCID 0000-0003-2317-4006

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
Optimizing health related quality of life measurement in adolescent and young adult oncology: A PROMISing solutionR01CA218398 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SALSMAN, JOHN · 2017 to 2021
$2.6M
iManageAYA: Preparation and Optimization of a mHealth Intervention for Managing Depressive Symptoms in Adolescent and Young adult Cancer SurvivorsR00CA248701 · NCI · EAST CAROLINA UNIVERSITY · PI MURPHY, KARLY MARY · 2023 to 2025
$630k
iManageAYA: Preparation and Optimization of a mHealth Intervention for Managing Depressive Symptoms in Adolescent and Young adult Cancer SurvivorsK99CA248701 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MURPHY, KARLY MARY · 2022 to 2023
$300k
NCI NIH HHS K99 CA248701NCI NIH HHS P30 CA012197NCI NIH HHS R00 CA248701NCI NIH HHS R01 CA218398
6 · The paper itself

Abstract

purposeFor adolescents and young adults (AYAs) with cancer, fertility preservation (FP) decision making is complex and distressing. Racial/ethnic minority (REM) AYAs experience disparities in FP awareness, uptake, and outcomes. A turning point (TP) is a point of reflection, change, or decisive moment(s) resulting in changes in perspectives or trajectories. To enhance understanding of AYAs' diverse experiences, this study examined alignment and/or divergence of FP decisional TPs among non-Hispanic White (NHW) AYAs and REM AYAs.

methodsQualitative semistructured interviews were conducted in person, by video, or phone with 36 AYAs (20 NHW and 16 REM [nine Hispanic and seven Black/multiracial Black). The constant comparative method was used to identify and analyze themes illustrating participants' conceptualization and/or experience of FP decisional TPs.

resultsSeven thematic TPs emerged: (1) emotional reaction to discovering FP procedures exist; (2) encountering unclear or dismissive communication during initial fertility conversations with health care providers; (3) encountering direct and supportive communication during initial fertility conversations with health care providers; (4) participating in critical family conversations about pursuing FP; (5) weighing personal desire for a child against other priorities/circumstances; (6) realizing FP is not feasible, and (7) experiencing unanticipated changes in cancer diagnosis or treatment plans/procedures. TP variations include REM participants reported dismissive communication and suggested cost was prohibitive. NHW participants emphasized more forcefully that biological children may become a future priority.

conclusionUnderstanding how clinical communication and priorities/resources may vary for NHW and REM AYAs can inform future interventions aimed at reducing health disparities and enhancing patient-centered care.

Indexed as

Fertility PreservationNeoplasmsAdolescentChildDecision MakingEthnicityHumansMinority GroupsYoung Adult

Identifiers

PMID37058685
PMCPMC10337714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.