Evidence map›Paper›PMID 37058246›Full record

ReviewBioprocess and biosystems engineering2023

Bioproduction and applications of aldobionic acids with a focus on maltobionic and cellobionic acid.

Emmeran Bieringer, Uxía García Vázquez, Luisa Klein, Núria Moretó Bravo, Matthias Tobler, Dirk Weuster-Botz

Open access · hybridAbstract readReview
In one paragraph

Review in Bioprocess and biosystems engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Emmeran BieringerTUM School of Engineering and Design, Department of Energy and Process Engineering, Chair of Biochemical Engineering, Technical University of Munich, Boltzmannstr. 15, 85748, Garching, Germany.ORCID http://orcid.org/0000-0001-8757-4450
Uxía García VázquezTUM School of Engineering and Design, Technical University of Munich, Boltzmannstraße 15, 85748, Garching, Germany.
Luisa KleinTUM School of Engineering and Design, Technical University of Munich, Boltzmannstraße 15, 85748, Garching, Germany.
Núria Moretó BravoTUM School of Natural Sciences, Technical University of Munich, Lichtenbergstraße 4, 85748, Garching, Germany.
Matthias ToblerTUM Campus Straubing for Biotechnology and Sustainability, Technical University of Munich, Petersgasse 5, 94315, Straubing, Germany.
Dirk Weuster-BotzTUM School of Engineering and Design, Department of Energy and Process Engineering, Chair of Biochemical Engineering, Technical University of Munich, Boltzmannstr. 15, 85748, Garching, Germany. dirk.weuster-botz@tum.de.
Technical University of Munich · DEStadtwerke Straubing (Germany) · DE

Funding

Bundesministerium für Ernährung und Landwirtschaft 2220NR129A
6 · The paper itself

Abstract

Aldobionic acids are sugar acids which consist of a disaccharide with an anomeric acid group. The most famous is lactobionic acid (LBA). LBA is used in many applications such as food and beverages, pharmaceuticals and medicine, cosmetics or chemical processes. During the last decade, all these industries are observing a shift of consumer preferences towards plant-based options. Thus, the biotechnological industry is trying to replace the animal-derived LBA. Maltobionic acid (MBA) and cellobionic acid (CBA) are two stereoisomers of LBA which have emerged as vegan alternatives. However, MBA and CBA face different obstacles related to their industrial production. While traditionally used electrochemical or chemical catalysis often rely on cost intensive and/or hazardous catalysts, novel production methods with microorganisms are still poorly studied. In the first part, this paper discusses both alternatives in terms of their characteristics and applications. In the second part, it reviews the long-studied chemical production and the novel bioproduction methods, which are based on enzymatic and microbial systems. This review concludes with a discussion of future work needed to bring their production to the industrial scale.

Indexed as

BiotechnologyDisaccharidesAnimalscellobionic acidDisaccharidesCellobionic acidEnzymatic biocatalysisMaltobionic acidPlant-based supplementsWhole-cell biocatalysis

Identifiers

PMID37058246
PMCPMC10239384
OpenAlexW4365479000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.