ReviewCurrent hypertension reports2023
Neurogenic Background for Emotional Stress-Associated Hypertension.
Review in Current hypertension reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 39 citations in OpenAlex.
- Improving Cardiometabolic Health in Adolescent Girls With Elevated Anxiety: Web-Based Multisite, Pilot, and Feasibility Randomized Controlled Trial.JMIR cardio · 2026Trial
- Associations of transitions in frailty and depressive symptoms with the risk of cardiovascular disease in adults with hypertension: findings from three aging cohorts.The journal of nutrition, health & aging · 2026Article
- Respiration Can Trigger Cerebrovascular Reactivity: A Novel Method to Quantify Cerebrovascular Resistance Dynamics Using Real-Time Phase-Contrast MRI.Magnetic resonance in medicine · 2026Article
- Neural Control of Tissue Perfusion: Emerging Evidence and Beyond.Current hypertension reports · 2026Review
- Association between stock market returns and outpatient visits for hypertension: evidence from a large city in East China.BMC public health · 2026Article
- A Neuroendocrine-Immune Model of Hidradenitis Suppurativa: Mechanistic Insights into Pain, Pruritus, and Hormonal Triggers.Journal of clinical medicine · 2026Review
- Psychological Burden in Uncontrolled Hypertension: Findings from the ERIDANO Multicenter Study.Journal of clinical medicine · 2026Article
- Nitrergic neurotransmission within the lateral hypothalamus modulates cardiovascular responses to stress in rats.Pflugers Archiv : European journal of physiology · 2026Article
- Chloride homeostasis dysfunction drives hyperactivation of corticotropin-releasing factor-expressing neurons in the amygdala in stress-induced hypertension.The Journal of clinical investigation · 2026Article
- Autonomic cardiovascular mechanisms linked to stress in dental practice.British dental journal · 2026Review
- TracMyAir: Smartphone-enabled spatiotemporal estimates for inhaled doses of particulate matter and ozone to personalize health outcomes.medRxiv : the preprint server for health sciences · 2026Article
- Psychophysiological correlates of professional experience among female teachers of secondary schools in Kazakhstan.PloS one · 2026Article
- Integration of laryngeal and cardiorespiratory control by the dorsomedial and perifornical hypothalamus in anaesthetised rats.Frontiers in neuroscience · 2026Article
- The Overlooked Driver of Hypertension: Mental Stress at the Crossroad of Cardiology and Psychiatry.Current atherosclerosis reports · 2025Review
- Chronic emotional stress and mediating role of Interleukin-6 in the association with cardiometabolic disorders in a multiethnic middle-aged and older US population.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Pathophysiologic Mechanisms of Cardiovascular Disease in Patients With Bipolar Disorder.Cureus · 2025Review
- Bridging gaps in risk factor control and adherence to recommended lifestyle among Non-Elderly hypertensive patients.Scientific reports · 2025Article
- The neuronal and glial cell diversity in the celiac ganglion revealed by single-nucleus RNA sequencing.Scientific reports · 2025Article
- Association between cardiometabolic index and hypertension among US adults from NHANES 1999-2020.Scientific reports · 2025Article
- Management of obesity in an individual with ROHHAD syndrome with semaglutide 2.4 mg/week: a case report.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
purpose of reviewThe response to natural stressors involves both cardiac stimulation and vascular changes, primarily triggered by increases in sympathetic activity. These effects lead to immediate flow redistribution that provides metabolic support to priority target organs combined with other key physiological responses and cognitive strategies, against stressor challenges. This extremely well-orchestrated response that was developed over millions of years of evolution is presently being challenged, over a short period of time. In this short review, we discuss the neurogenic background for the origin of emotional stress-induced hypertension, focusing on sympathetic pathways from related findings in humans and animals. RECENT
findingsThe urban environment offers a variety of psychological stressors. Real or anticipatory, emotional stressors may increase baseline sympathetic activity. From routine day-to-day traffic stress to job-related anxiety, chronic or abnormal increases in sympathetic activity caused by emotional stressors can lead to cardiovascular events, including cardiac arrhythmias, increases in blood pressure and even sudden death. Among the various alterations proposed, chronic stress could modify neuroglial circuits or compromise antioxidant systems that may alter the responsiveness of neurons to stressful stimuli. These phenomena lead to increases in sympathetic activity, hypertension and consequent cardiovascular diseases. The link between anxiety, emotional stress, and hypertension may result from an altered neuronal firing rate in central pathways controlling sympathetic activity. The participation of neuroglial and oxidative mechanisms in altered neuronal function is primarily involved in enhanced sympathetic outflow. The significance of the insular cortex-dorsomedial hypothalamic pathway in the evolution of enhanced overall sympathetic outflow is discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.