Evidence map›Paper›PMID 37058192›Full record

ArticleEnvironmental geochemistry and health2023

Closing the knowledge gap on the composition of the asbestos bodies.

F Bardelli, C Giacobbe, P Ballirano, V Borelli, F Di Benedetto, G Montegrossi, D Bellis, A Pacella

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental geochemistry and health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Mosses in Urban Environments as Passive Biofilters and Organisms Impacted by Asbestos-Contaminated Habitats.International journal of environmental research and public health · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

F BardelliNational Research Council, Institute of Nanotechnology (CNR-Nanotec), Rome, Italy. fabrizio.bardelli@cnr.it.
C GiacobbeXenocs SAS, Grenoble, France.
P BalliranoDepartment of Earth Sciences, La Sapienza University, Rome, Italy.
V BorelliDepartment of Physiology and Pathology, University of Trieste, Trieste, Italy.
F Di BenedettoDepartment of Earth Sciences, University of Ferrara, Ferrara, Italy.
G MontegrossiNational Research Council, Institute of Geoscience and Earth Resources (CNR-IGG), Florence, Italy.
D BellisCentre for the Study of Asbestos and Other Toxic Particulate, University of Torino, Turin, Italy.
A PacellaDepartment of Earth Sciences, La Sapienza University, Rome, Italy.
Sapienza University of Rome · ITEuropean Synchrotron Radiation Facility · FRIstituto Nanoscienze · ITNational Research Council · ITUniversity of Ferrara · ITUniversity of Trieste · ITUniversity of Turin · IT

Funding

Istituto Nazionale per l'Assicurazione Contro Gli Infortuni sul Lavoro BRIC2019, ID57
6 · The paper itself

Abstract

Asbestos bodies (AB) form in the lungs as a result of a biomineralization process initiated by the alveolar macrophages in the attempt to remove asbestos. During this process, organic and inorganic material deposit on the foreign fibers forming a Fe-rich coating. The AB start to form in months, thus quickly becoming the actual interface between asbestos and the lung tissue. Therefore, revealing their composition, and, in particular, the chemical form of Fe, which is the major component of the AB, is essential to assess their possible role in the pathogenesis of asbestos-related diseases. In this work we report the result of the first x-ray diffraction measurements performed on single AB embedded in the lung tissue samples of former asbestos plant workers. The combination with x-ray absorption spectroscopy data allowed to unambiguously reveal that Fe is present in the AB in the form of two Fe-oxy(hydroxides): ferrihydrite and goethite. The presence of goethite, which can be explained in terms of the transformation of ferrihydrite (a metastable phase) due to the acidic conditions induced by the alveolar macrophages in their attempt to phagocytose the fibers, has toxicological implications that are discussed in the paper.

Indexed as

AsbestosAsbestosisFerric CompoundsHumansIron CompoundsLungMineralsAsbestosFerric Compoundsferric oxyhydroxidegoethiteIron CompoundsMineralsAsbestos bodiesFerrihydriteGoethiteIronMesotheliomaSynchrotron radiationToxicology

Identifiers

PMID37058192
PMCPMC10310571
OpenAlexW4365484860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.