Evidence map›Paper›PMID 37057765›Full record

SynthesisHuman vaccines & immunotherapeutics2023

A systematic review and meta-analysis of the seroconversion rates and adverse effects of COVID-19 mRNA vaccine and COVID-19 viral vector vaccine in kidney transplant recipient patients.

Sikai Chen, Wenxin Wei, Fengyu Huang, Jing Wang, Xingyu Li, Zhixin Geng, Feng Gao, Taiwei Dong, Peifeng Wei, Xinbo Yang and 1 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Human vaccines & immunotherapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Sikai ChenCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Wenxin WeiQueen Mary College, Nanchang University School of Medicine, Nanchang, China.
Fengyu HuangCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Jing WangCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Xingyu LiCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Zhixin GengCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Feng GaoCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Taiwei DongCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Peifeng WeiCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Xinbo YangSecond Clinical School of Medicine, Shaanxi University of Chinese Medicine, Xianyang, China.
Feng MiaoThe Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, China.
Shaanxi University of Chinese Medicine · CNAffiliated Hospital of Shaanxi University of Chinese Medicine · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients received kidney transplantation (KTR) have a low seroconversion rate after vaccination. Our objective was to compare the seroconversion rates and adverse effects of additional different vaccinations in KTR patients in existing studies. Databases such as PubMed, Cochrane Library, Web of Science, Embase, ClinicalTrials.gov and others. Three high-quality RCT were included and showed no statistical difference in seroconversion rates between the two vaccines (RR = 0.93[0.76,1.13]). There was no statistical difference in seroconversion rates between the sexes, for men (RR = 0.93[0.69,1.25]) and women (RR = 0.91[0.62,1.33]). Among the adverse effects there was no statistically significant difference in fever (RR = 1.06[0.44,2.57]), while for injection site pain there was a statistically significant difference (RR = 1.14[1.18,1.84]). There was no significant difference in seroconversion rates in patients with KTR who received the two additional vaccines. Patients injected with the viral vector vaccine were less painful than those injected with the mRNA vaccine.

Indexed as

COVID-19COVID-19 VaccinesKidney TransplantationAntibodies, ViralFemaleHumansMaleSeroconversionVaccinationAntibodies, ViralCOVID-19 Vaccinesadverse effectsCOVID-19kidney transplant recipientmRNA vaccineseroconversion rateviral vector vaccine

Identifiers

PMID37057765
PMCPMC10120468
OpenAlexW4365483665

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.