ArticleOrthopaedic surgery2023
Gait Asymmetry Variation in Kinematics, Kinetics, and Muscle Force along with the Severity Levels of Knee Osteoarthritis.
Article in Orthopaedic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Inter-Session Repeatability of a Smartphone-Based Markerless System to Measure Segment Length and Lower-Limb Kinematics in Patients With End-Stage Knee Osteoarthritis.Orthopaedic surgery · 2026Article
- Comparison of Joint Kinematics and Spatiotemporal Gait Parameters Between Markerless and Marker-Based Motion Capture in a Large Knee Osteoarthritis Cohort.Annals of biomedical engineering · 2026Article
- Gait Biomechanics, Symmetry Restoration, and Functional Recovery Following Total Knee Arthroplasty: A Prospective Longitudinal Cohort Study.Life (Basel, Switzerland) · 2026Article
- Gait Asymmetry in Arm Swing and Foot Progression Angle of Knee Osteoarthritis.Journal of clinical medicine · 2026Article
- Radiographic Analysis of Lower Limb Alignment in Patients with Knee Osteoarthritis.Tomography (Ann Arbor, Mich.) · 2026Article
- Associations of muscle coactivation patterns with gait, muscle strength, and symptoms across different stages of knee osteoarthritis.Knee surgery & related research · 2026Article
- Wireless knee joint monitoring using biodegradable single-ended pressure sensor in osteoarthritis management.Science advances · 2026Article
- Asymmetrical biomechanics in knee osteoarthritis: a review of contralateral risk from primary disease to post-arthroplasty progression.EFORT open reviews · 2026Review
- Association between the sarcopenia index and osteoarthritis: a cross-sectional and longitudinal study.European journal of medical research · 2026Article
- Gait asymmetry as a determinant of functional recovery and return to sport after ACL reconstruction: a cross-sectional biomechanical analysis.Frontiers in bioengineering and biotechnology · 2026Article
- A retrospective predictive model for worsening knee osteoarthritis pain by integrating baseline gait biomechanics and wearable gait parameters.American journal of translational research · 2026Article
- Open Versus Closed Kinetic Chain: Exercise Effects on Center of Pressure and Y-Balance in Middle-Aged Women with Knee Osteoarthritis-A Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2025Article
- Artificial intelligence-based analysis of lower limb muscle mass and fatty degeneration in patients with knee osteoarthritis and its correlation with Knee Society Score.International journal of computer assisted radiology and surgery · 2025Article
- Gender differences in peak medial joint contact forces during activities of daily living.PeerJ · 2025Article
- The Effect of Thigh Muscle Forces on Knee Contact Force in Female Patients with Severe Knee Osteoarthritis.Bioengineering (Basel, Switzerland) · 2024Article
- Portable Gait Analysis of Patients With Rotating Hinge Knee Megaprosthesis Compared With Total Knee Arthroplasty.Orthopaedic surgery · 2024Article
- Analysis of Risk Factors on Patellofemoral Osteoarthritis: Distribution Characteristics and Radiographic Parameters of Patellofemoral Joint.Orthopaedic surgery · 2024Article
- Influencing factors analysis of asymmetry in knee adduction moment among patients with unilateral knee osteoarthritis.BMC musculoskeletal disorders · 2024Article
- Pedaling Asymmetry Reflected by Bilateral EMG Complexity in Chronic Stroke.Entropy (Basel, Switzerland) · 2024Article
- A Radiographic Analysis of Coronal Morphological Parameters of Lower Limbs in Chinese Non-knee Osteoarthritis Populations.Orthopaedic surgery · 2024Article
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Authors and funding
9 authors.
Funding
Abstract
objectiveKnee osteoarthritis (OA) patients exhibit greater gait asymmetry than healthy controls. However, gait asymmetry in kinematics, kinetics and muscle forces across patients with different severity levels of knee OA is still unknown. The study aimed to investigate the changes of gait asymmetry in lower limb kinematics, kinetics, and muscle force across patients with different severity levels of knee OA.
methodsThis is a cross-sectional study. From January 2020 to January 2021, 118 patients with symptomatic and radiographic medial knee OA were categorized into three groups using the Kellgren and Lawrence scale (mild: grade 1 and 2, n = 37; moderate: grade 3, n = 31; severe: grade 4, n = 50). During self-paced walking, marker trajectories and ground reaction forces data were recorded. Musculoskeletal simulations were used to determine gait kinematics, kinetics, and muscle force. One-way analysis of variance with Tukey's post-hoc test was used to evaluate group difference. Paired-sample t-test was used to compared the between-limb difference.
resultsIn the Severe group, significantly greater asymmetry index in knee flexion/extension range of motion (45%) was observed with a greater value on the contralateral side (p < 0.01), compared to the Mild (15%) and Moderate (15%) groups. Significantly higher peak hip contact force (JCF) on the contralateral side was found in the Mild (more affected side: 3.80 ± 0.67 BW, contralateral side: 4.01 ± 0.58 BW), Moderate (more affected side: 3.67 ± 0.56 BW, contralateral side: 4.07 ± 0.81 BW), and Severe groups (more affected side: 3.66 ± 0.79 BW, contralateral side: 3.94 ± 0.64 BW) (p < 0.05). Significantly greater gluteus medius muscle force on the contralateral side was found in Mild (more affected side: 0.48 ± 0.09 BW, contralateral side: 0.52 ± 0.12 BW), Moderate (more affected side: 0.45 ± 0.10 BW, contralateral side: 0.51 ± 0.15 BW), and Severe groups (more affected side: 0.42 ± 0.15 BW, contralateral side: 0.47 ± 0.12 BW) (p < 0.05). The contralateral side showing significantly higher peak knee adduction moment and medial knee JCF was only observed in the Mild group (p < 0.05).
conclusionsGait asymmetry in kinematics and muscle forces increased from mild to severe knee OA. Asymmetrical gait pattern tends to transfer loads from the more affected side to the contralateral side. Peak hip JCF and gluteus medius muscle force can be used to detect this asymmetrical gait pattern in patients with knee OA, regardless of severity levels.
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