Evidence map›Paper›PMID 37057304›Full record

SynthesisIntegrative cancer therapies

Effects of Traditional Chinese Medicine Injections for Anthracyclines-induced Cardiotoxicity: An Overview of Systematic Reviews and Meta-Analyses.

Chenchen Li, Yuling Zheng, Dong Niu, Ranpei Zhu, Xiaoyu Yan, Haoran Qu, Yaling Zhang

Open access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Chenchen LiThe First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou, Henan Province, China.ORCID 0000-0003-3848-4162
Yuling ZhengThe First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou, Henan Province, China.
Dong NiuThe First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou, Henan Province, China.
Ranpei ZhuThe First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou, Henan Province, China.
Xiaoyu YanThe First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou, Henan Province, China.
Haoran QuThe First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou, Henan Province, China.
Yaling ZhangThe First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan Province, China.
First Affiliated Hospital of Henan University · CNFirst Affiliated Hospital of Henan University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTraditional Chinese medicine (TCM) injections, as a relatively safe and low-cost treatment, have been widely used in the prevention and treatment of anthracyclines-induced cardiotoxicity in China. However, the quality of the relevant systematic reviews and meta-analyses published in recent years is uneven, so that the effectiveness and safety of TCM injections in preventing and treating anthracyclines-induced cardiotoxicity remain to be discussed. A systematic overview is therefore needed to provide a more advanced evidentiary reference for clinical practice.

methodsEight Chinese and English databases were searched by computer to screen the meta-analyses/systematic reviews on the efficacy of traditional Chinese medicine injections for the prevention and treatment of anthracyclines-induced cardiotoxicity from the database establishment to October 2022. The methodological quality and evidence quality of outcome indicators included in the study were evaluated by AMSTAR 2 tool, PRISMA statement and GRADE classification.

resultsA total of 7 articles were included in the study. The quality evaluation of AMSTAR 2 showed that 7 studies were extremely low-level; PRISMA stated that the evaluation results showed that the reports of 7 studies were of intermediate quality; The GRADE rating indicated that most of the evidence was of low quality.

conclusionThe methodological quality and evidence quality of meta-analysis/system evaluation concerning the prevention and treatment of anthracyclines-induced cardiotoxicity by Chinese medicine are currently low, and the effectiveness of Chinese medicine in the treatment of anthracyclines-induced cardiotoxicity needs more high-quality evidence-based evidence.

Indexed as

AnthracyclinesCardiotoxicityDrugs, Chinese HerbalAntibiotics, AntineoplasticHumansMedicine, Chinese TraditionalAnthracyclinesAntibiotics, AntineoplasticDrugs, Chinese HerbalAnthracyclinesCardiac toxicityChinese medicine injectionOverviewTCM

Identifiers

PMID37057304
PMCPMC10108409
OpenAlexW4365479085

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.