Evidence map›Paper›PMID 37057292›Full record

ArticleJournal of Cancer2023

Visualizing intratumoral injections in lung tumors by endobronchial ultrasound.

Vitor Mori, Emily A DuComb, Sarah Wagner, Farrah Khan, Jason H T Bates, C Matthew Kinsey

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06686043 (A Phase 2 Study of HPV L1 Vaccine in Combination With Imiquimod and Metformin in Cervical, Vaginal, and Vulvar Cancers), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06686043 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

A Phase 2 Study of HPV L1 Vaccine in Combination With Imiquimod and Metformin in Cervical, Vaginal, and Vulvar Cancers

TypeinterventionalSponsorBaylor College of MedicineRan2024 to 2028Enrolled85ConditionsCervical Carcinoma, Vaginal Carcinoma, Vulvar Carcinoma, HPV (Human Papillomavirus)-Associated CarcinomaArmsHPV vaccine, Imiquimod, and metformin combination therapy
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. The effect of oncolytic virotherapy on pediatric brain tumor- a systematic review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Pooled it
  2. Fracking in Tumors: A Key Drug Transport Mechanism.Annals of biomedical engineering · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Vitor MoriVermont Lung Center, Pulmonary and Critical Care Medicine, Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05405, USA.
Emily A DuCombVermont Lung Center, Pulmonary and Critical Care Medicine, Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05405, USA.
Sarah WagnerVermont Lung Center, Pulmonary and Critical Care Medicine, Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05405, USA.
Farrah KhanDivision of Hematology and Oncology, Department of Medicine, University of Vermont, Burlington VT 05405.
Jason H T BatesVermont Lung Center, Pulmonary and Critical Care Medicine, Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05405, USA.
C Matthew KinseyVermont Lung Center, Pulmonary and Critical Care Medicine, Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05405, USA.
University of Vermont · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Real-time endobronchial ultrasound images are crucial for the accurate placement of the needle in peribronchial lung tumors and lymph nodes for diagnostic sampling. Beyond its role as a diagnostic tool, ultrasound-guided bronchoscopy can also aid the delivery of anti-cancer agents intratumorally, enabling diagnosis, staging, and treatment to occur within the same anesthesia, reducing the patient's burden. However, determining drug retention and distribution

Indexed as

Drug DynamicsEBUS-TBNIIntratumoral Chemotherapy

Identifiers

PMID37057292
PMCPMC10088536
OpenAlexW4324009853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.