Evidence map›Paper›PMID 37057069›Full record

ArticleFrontiers in nutrition2023

Determinants of human milk oligosaccharides profiles of participants in the STRONG kids 2 cohort.

Yuting Fan, Anita Vinjamuri, Diane Tu, Carlito B Lebrilla, Sharon M Donovan

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03341858 (STRONG Kids 2), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03341858 active not recruitingnot on this map

STRONG Kids 2: A Cells-to-Society Approach to Nutrition in Early Childhood

TypeobservationalSponsorUniversity of Illinois at Urbana-ChampaignRan2013 to 2029Enrolled450ConditionsChild Obesity, Child, OnlyArmsno intervention-strictly observational
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Effects of maternal allergy and supplementation with ω-3 fatty acid and probiotic on human milk oligosaccharides.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yuting FanDepartment of Food Science and Human Nutrition, University of Illinois, Urbana, IL, United States.
Anita VinjamuriDepartment of Chemistry, University of California, Davis, Davis, CA, United States.
Diane TuDepartment of Chemistry, University of California, Davis, Davis, CA, United States.
Carlito B LebrillaDepartment of Chemistry, University of California, Davis, Davis, CA, United States.
Sharon M DonovanDepartment of Food Science and Human Nutrition, University of Illinois, Urbana, IL, United States.
University of California, Davis · USUniversity of Illinois Urbana-Champaign · US

Funding

Dietary and microbial predictors of childhood obesity riskR01DK107561 · NIDDK · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CHAPKIN, ROBERT STEPHEN, DONOVAN, SHARON MARIE · 2017 to 2021
$2.8M
NIDDK NIH HHS R01 DK107561
6 · The paper itself

Abstract

Introduction: Human milk oligosaccharides (HMOS) are indigestible carbohydrates that support infant development by establishing a healthy microbiota, preventing infectious diseases, and promoting immune and cognitive development. Individual HMOS have distinct functions based on their chemical structures. HMO profiles can vary largely among mothers, but the research on factors other than genetic background affecting HMO composition are limited. Methods: In the present analysis, we examined the relationships between maternal characteristics and the HMO profiles of breastfeeding mothers ( Results: Among all participants, 71.9% were secretors and 28.1% were non-secretors. The relative abundances of all HMOS differed ( Discussion: HMO profiles were found to be associated with maternal characteristics and intake. Future research will investigate associations between HMOS and maternal and infant outcomes.

Indexed as

human milkhuman milk oligosaccharidesmaternal intakesecretor statusweight status

Identifiers

PMID37057069
PMCPMC10086122
OpenAlexW4361221287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.