ArticleAmerican journal of translational research2023
The clinical value of prenatal ultrasound in the diagnosis of caudal regression syndrome.
Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- Familial caudal regression syndrome with complex spinal dysraphism presenting as recurrent cutaneous infection.Surgical neurology international · 2026Article
- Long-term outcomes in sacral agenesis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Caudal Regression Syndrome First Diagnosed in Adulthood: A Case Report and a Review of the Literature.Diagnostics (Basel, Switzerland) · 2024Article
- Sirenomelia or mermaid syndrome with a cleft lip in a Tanzanian newborn: a case report.Journal of medical case reports · 2024Article
- Congenital Anterior Dislocation of the Sacrococcygeal Bone in a Newborn.Diagnostics (Basel, Switzerland) · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCaudal regression syndrome (CRS) is a rare and fatal anomaly that can easily be missed in prenatal two-dimensional (2D) ultrasonography. This retrospective analysis aimed to determine the performance of combined 2D and three-dimensional (3D) ultrasound for the prenatal diagnosis of CRS.
methodsWe retrospectively analyzed 168 fetuses diagnosed with spinal lesions by combined 2D and 3D ultrasound at the First Affiliated Hospital of Anhui Medical University from January 2016 to June 2022. We analyzed the sonographic characteristics of these cases and assessed the diagnostic value of ultrasound in fetal CRS.
resultsFourteen fetuses were confirmed to have CRS after labor induction and postpartum, and 13 of these were correctly identified by prenatal ultrasound imaging. The sensitivity, specificity, accuracy, and Youden index of prenatal ultrasound were 85.7%, 93.5%, 92.9%, and 0.79, respectively.
conclusionThe typical prenatal sonographic features of CRS include different degrees of lumbar and sacrococcygeal spine loss combined with abnormal lower limb development. Prenatal ultrasound can assess the extent and location of lesions, highlighting its high diagnostic value.
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37056862PMC10086933W4365483211What OpenQuestion holds
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