Evidence map›Paper›PMID 37056858›Full record

ArticleAmerican journal of translational research2023

Characteristics and associations of microbial community in the eye, anterior nares, and oropharynx of healthy adults: eye-nose microbiota transmission.

Xinxin Zhang, Kui Dong, Zhiming Kang, Xuan Ji, Xiaoling Ning, Qin Ma, Bin Sun

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xinxin ZhangShanxi Eye Hospital Affiliated to Shanxi Medical University Taiyuan 030002, Shanxi, China.
Kui DongShanxi Eye Hospital Affiliated to Shanxi Medical University Taiyuan 030002, Shanxi, China.
Zhiming KangShanxi Eye Hospital Affiliated to Shanxi Medical University Taiyuan 030002, Shanxi, China.
Xuan JiShanxi Eye Hospital Affiliated to Shanxi Medical University Taiyuan 030002, Shanxi, China.
Xiaoling NingShanxi Eye Hospital Affiliated to Shanxi Medical University Taiyuan 030002, Shanxi, China.
Qin MaShanxi Eye Hospital Affiliated to Shanxi Medical University Taiyuan 030002, Shanxi, China.
Bin SunShanxi Eye Hospital Affiliated to Shanxi Medical University Taiyuan 030002, Shanxi, China.
Shanxi Eye Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe compared the microbial communities of the eye, anterior nares (ANs) and oropharynx (OP) of healthy adults to provide a basic understanding of the microbial associations among the three sites.

methodsThe name of the registry of our prospective study was "Study on the diversity of microbial flora in the eye, nose and oropharynx of healthy people". The trial number is ChiCTR2300067724 (https://www.chictr.org.cn/index.aspx). Swabs were collected from the eye, ANs and OP of 48 healthy adult participants for 16S rRNA gene amplicon sequencing. The bacterial community profiles and their functional associations were compared among the three sites.

resultsAt a phylum level, the basic bacterial compositions in the eye and ANs were generally similar, and the predominant phyla were

conclusionsThe bacterial flora composition and function predictions of eye and ANs were similar, but differed from those of the OP in healthy adults. The OP bacterial flora distribution was markedly different, showing characteristics similar to that of the digestive tract flora. Thus, the eye and ANs microorganisms may be related in healthy individuals.

Indexed as

16S rRNA gene sequencingbacterial transmissionnose microbiotaOcular surface microbiota

Identifiers

PMID37056858
PMCPMC10086891
OpenAlexW4365479714

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.