Evidence map›Paper›PMID 37056853›Full record

ArticleAmerican journal of translational research2023

Clinical and prognostic significance of long non-coding RNA CRNDE expression in severe pneumonia and its correlation with inflammatory factor levels.

Miaomiao Peng, Lei Ma

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Miaomiao PengDepartment of Critical Care Medicine, Zibo Central Hospital Zibo 255036, Shandong, China.
Lei MaDepartment of Critical Care Medicine, Zibo Central Hospital Zibo 255036, Shandong, China.
Central Hospital of Zibo · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the clinical and prognostic significance of long non-coding RNA (lncRNA) CRNDE expression in severe pneumonia and its correlation with the levels of inflammatory factors.

methodsIn this retrospective study, 86 patients with severe pneumonia were selected as the observation group (OG), and 70 patients with non-severe pneumonia were selected as the control group (CG). The expression of lncRNA CRNDE was measured by real-time fluorescence quantitative reverse transcription polymerase chain reaction. The relationship between lncRNA CRNDE expression and clinical characteristics and prognosis of patients was analyzed. The correlation between lncRNA CRNDE expression and the levels of inflammatory factors related to severe pneumonia was also analyzed.

resultsRelative expression of lncRNA CRNDE in OG was significantly higher than that in CG (

conclusionslncRNA CRNDE is highly expressed in the serum of patients with severe pneumonia and is an independent risk factor for the poor prognosis of these patients. The expression of lncRNA CRNDE is also positively correlated with the levels of inflammatory factors in such patients, which can be used for the clinical detection of severe pneumonia.

Indexed as

clinicalinflammatory factorlncRNA CRNDEprognosissevere pneumonia

Identifiers

PMID37056853
PMCPMC10086886
OpenAlexW4365483433

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.