ArticleAmerican journal of translational research2023
Association of CT phenotype with pulmonary function in patients with chronic obstructive pulmonary disease and influencing factors of prognosis.
Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.
- Prevalence of non-smoking chronic obstructive pulmonary disease and its risk factors in China: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Clinical and Functional Heterogeneity of COPD Phenotypes: A Multicenter Study from Turkey (DIPTUR Study).Medicina (Kaunas, Lithuania) · 2026Observational
- Cardiopulmonary Exercise Testing and Quantitative Chest CT in COPD: The Stronger Association of Emphysema Over Airway Thickness with Functional Impairment.International journal of chronic obstructive pulmonary disease · 2026Article
- Quantitative CT evaluation of extrapulmonary lesions in chronic obstructive pulmonary disease: a narrative review.Journal of thoracic disease · 2025Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the correlation between computed tomography (CT) phenotype and pulmonary function in patients with chronic obstructive pulmonary disease (COPD) and to analyze the influencing factors of prognosis.
methodsIn this retrospective study, a total of 174 COPD patients admitted to the First Affiliated Hospital of Hebei North University from May 2017 to October 2020 were enrolled and assigned to the M-type group (n = 48), E-type group (n = 56) or A-type group (n = 70) according to their CT features. The CT features and pulmonary function indexes of all the patients and their correlation were analyzed, and the acute exacerbation in one-year follow-up of the patients was recorded. Logistic regression was carried out to analyze the influencing factors for the prognosis of COPD.
resultsThe A-type group showed significantly better pulmonary function than the E-type group and M-type group (P < 0.05), and the degree of emphysema was negatively correlated with pulmonary function. The A-type group showed a significantly lower one-year acute exacerbation rate than the other two groups (P < 0.05). A relatively longer course of disease, a relatively lower forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) ratio and CT phenotype were correlated with the unfavorable prognosis of patients.
conclusionAccording to determination of the pulmonary function of patients with COPD through CT, the degree of emphysema worsens with the progression of the disease. A relatively longer course of disease, a relatively lower FEV1/FVC ratio and CT phenotype are independent risk factors for unfavorable prognosis of COPD patients.
Indexed as
Identifiers
37056846PMC10086914W4365483000What OpenQuestion holds
Registered trials
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