ArticleAmerican journal of translational research2023
A cross-sectional study on gut microbiota in patients with chronic kidney disease undergoing kidney transplant or hemodialysis.
Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
8 citing papers in PubMed, 6 citations in OpenAlex.
- IgA-Producing B Cells Exert Regulatory Function through Granzyme B in Kidney Allograft Tolerance.Kidney360 · 2026Observational
- Impact of drug-induced immunosuppression following kidney transplantation on periodontal health and the periodontal microbiome: a longitudinal controlled study.Clinical oral investigations · 2026Article
- Identification of Gut Microbiome Signatures Associated with Serotonin Pathway in Tryptophan Metabolism of Patients Undergoing Hemodialysis.International journal of molecular sciences · 2025Article
- Article
- Gut Microbial Dysbiosis and Implications in Solid Organ Transplantation.Biomedicines · 2024Review
- Gut Microbiota in Patients Receiving Dialysis: A Review.Pathogens (Basel, Switzerland) · 2024Review
- Unraveling Intestinal Microbial Shifts in ESRD and Kidney Transplantation: Implications for Disease-Related Dysbiosis.Microorganisms · 2023Article
- Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate whether the gut microbiota differs in patients with chronic kidney disease receiving kidney transplant or hemodialysis, and to explore the relationship between the gut microbiota and clinical indicators.
methodsA total of 72 patients with kidney transplantation (RT) and 78 patients with hemodialysis (HD) admitted to the First Affiliated Hospital of Soochow University from January 2019 to October 2022 were selected as the research subjects. The V3-V4 region sequences of 16S rRNA were used for high-throughput sequencing to analyze the differences in gut microbiome between the two groups and its relationship with clinical indicators.
resultsGut microbial α diversity (Chao1, Ace, Shannon, Simpson) was significantly decreased in RT patients compared with that in HD patients (P<0.05). The relative abundance of
conclusionThis study elucidates the composition and changes of the gut microbiota in RT and HD patients and its association with clinical indicators, providing a scientific basis for the regulatory mechanism of gut microbiota in the treatment of chronic kidney disease.
Indexed as
Identifiers
37056836PMC10086930W4365482885What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.