Evidence map›Paper›PMID 37056490›Full record

ReviewFrontiers in plant science2023

Plant-made vaccines against viral diseases in humans and farm animals.

Hang Su, André van Eerde, Espen Rimstad, Ralph Bock, Norica Branza-Nichita, Igor A Yakovlev, Jihong Liu Clarke

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in plant science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
15.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Transient expression of human interleukin-15 inPlant biotechnology (Tokyo, Japan) · 2025
    Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Hang SuDivision of Biotechnology and Plant Health, NIBIO - Norwegian Institute of Bioeconomy Research, Ås, Norway.
André van EerdeDivision of Biotechnology and Plant Health, NIBIO - Norwegian Institute of Bioeconomy Research, Ås, Norway.
Espen RimstadFaculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.
Ralph BockDepartment III, Max Planck Institute of Molecular Plant Physiology, Potsdam-Golm, Germany.
Norica Branza-NichitaDepartment of Viral Glycoproteins, Institute of Biochemistry of the Romanian Academy, Bucharest, Romania.
Igor A YakovlevDivision of Biotechnology and Plant Health, NIBIO - Norwegian Institute of Bioeconomy Research, Ås, Norway.
Jihong Liu ClarkeDivision of Biotechnology and Plant Health, NIBIO - Norwegian Institute of Bioeconomy Research, Ås, Norway.
Norwegian Institute of Bioeconomy Research · NOMax Planck Institute of Molecular Plant Physiology · DENorwegian University of Life Sciences · NORomanian Academy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants provide not only food and feed, but also herbal medicines and various raw materials for industry. Moreover, plants can be green factories producing high value bioproducts such as biopharmaceuticals and vaccines. Advantages of plant-based production platforms include easy scale-up, cost effectiveness, and high safety as plants are not hosts for human and animal pathogens. Plant cells perform many post-translational modifications that are present in humans and animals and can be essential for biological activity of produced recombinant proteins. Stimulated by progress in plant transformation technologies, substantial efforts have been made in both the public and the private sectors to develop plant-based vaccine production platforms. Recent promising examples include plant-made vaccines against COVID-19 and Ebola. The COVIFENZ

Indexed as

farm animalshumansmolecular farmingplant-made vaccinesplant transformationviral diseases

Identifiers

PMID37056490
PMCPMC10086147
OpenAlexW4361222187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.