Evidence map›Paper›PMID 37056476›Full record

ArticleBrain communications2023

Comparing the brain-behaviour relationship in acute and chronic stroke aphasia.

Natalie Busby, Argye E Hillis, Lisa Bunker, Chis Rorden, Roger Newman-Norlund, Leo Bonilha, Erin Meier, Emily Goldberg, Gregory Hickok, Grigori Yourganov and 1 more

Abstract read
In one paragraph

Article in Brain communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Natalie BusbyDepartment of Communication Sciences and Disorders, University of South Carolina, Columbia, SC 29209, USA.ORCID https://orcid.org/0000-0001-7117-7899
Argye E HillisDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, MA 21287, USA.ORCID https://orcid.org/0000-0002-5192-1171
Lisa BunkerDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, MA 21287, USA.ORCID https://orcid.org/0000-0001-9637-3204
Chis RordenDepartment of Psychology, University of South Carolina, Columbia, SC 29208, USA.
Roger Newman-NorlundDepartment of Communication Sciences and Disorders, University of South Carolina, Columbia, SC 29209, USA.
Leo BonilhaDepartment of Neurology, Emory University, Atlanta, GA 30322, USA.
Erin MeierDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, MA 21287, USA.
Emily GoldbergDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, MA 21287, USA.
Gregory HickokDepartment of Cognitive Sciences, University of California, Irvine, CA 92697, USA.ORCID https://orcid.org/0000-0003-0901-5527
Grigori YourganovAdvanced Computing and Data Science, Cyberinfrastructure and Technology Integration, Clemson University, Clemson, SC 29634, USA.
Julius FridrikssonDepartment of Communication Sciences and Disorders, University of South Carolina, Columbia, SC 29209, USA.

Funding

Telerehab for Aphasia (TERRA)P50DC014664 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FRIDRIKSSON, JULIUS · 2016 to 2025
$25.0M
NIDCD NIH HHS P50 DC014664
6 · The paper itself

Abstract

In stroke aphasia, lesion volume is typically associated with aphasia severity. Although this relationship is likely present throughout recovery, different factors may affect lesion volume and behaviour early into recovery (acute) and in the later stages of recovery (chronic). Therefore, studies typically separate patients into two groups (acute/chronic), and this is often accompanied with arguments for and against using data from acute stroke patients over chronic. However, no comprehensive studies have provided strong evidence of whether the lesion-behaviour relationship early in recovery is comparable to later in the recovery trajectory. To that end, we investigated two aims: (i) whether lesion data from acute and chronic patients yield similar results in region-based lesion-symptom mapping analyses and (ii) if models based on one timepoint accurately predict the other. Lesions and aphasia severity scores from acute (

Indexed as

acuteaphasiachroniclesionstroke

Identifiers

PMID37056476
PMCPMC10088484

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.