Evidence map›Paper›PMID 37056370›Full record

ArticleCell reports methods2023

A single-copy knockin translating ribosome immunoprecipitation toolkit for tissue-specific profiling of actively translated mRNAs in

Laura E Wester, Anne Lanjuin, Emanuel H W Bruckisch, Maria C Perez-Matos, Peter G Stine, Caroline Heintz, Martin S Denzel, William B Mair

Open access · goldAbstract read
In one paragraph

Article in Cell reports methods, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Laura E WesterDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Anne LanjuinDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Emanuel H W BruckischDepartment of Molecular Genetics of Ageing, Max Planck Institute for Biology of Ageing, 50668 Cologne, Germany.
Maria C Perez-MatosDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Peter G StineDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Caroline HeintzDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Martin S DenzelDepartment of Molecular Genetics of Ageing, Max Planck Institute for Biology of Ageing, 50668 Cologne, Germany.
William B MairDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Harvard University · USMax Planck Institute for Biology of Ageing · DE

Funding

Mechanisms Specific to the Beneficial Effects of Dietary RestrictionR01AG044346 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI William B Mair · 2013 to 2026
$3.8M
Cell Non-autonomous Regulation of Aging via Neuronal TORC1R01AG059595 · NIA · HARVARD SCHOOL OF PUBLIC HEALTH · PI MAIR, WILLIAM B · 2018 to 2022
$2.0M
Reversing Loss of Metabolic Homeostasis to Ameliorate Alzheimer's Disease PathogenicityR01AG067106 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI MAIR, WILLIAM B · 2020 to 2024
$2.0M
Targeting RNA homeostasis to promote healthy agingR01AG051954 · NIA · HARVARD SCHOOL OF PUBLIC HEALTH · PI MAIR, WILLIAM B · 2017 to 2020
$1.7M
NIA NIH HHS R01 AG044346NIA NIH HHS R01 AG051954NIA NIH HHS R01 AG059595NIA NIH HHS R01 AG067106
6 · The paper itself

Abstract

Here, we introduce a single-copy knockin translating ribosome immunoprecipitation (SKI TRIP) toolkit, a collection of

Indexed as

Caenorhabditis elegansProtein BiosynthesisAnimalsImmunoprecipitationRibosomal ProteinsRibosomesRNA, MessengerRibosomal ProteinsRNA, MessengerC. elegansribotagRPL-22SKI TRIPtranslationtranslatomeTRAP

Identifiers

PMID37056370
PMCPMC10088236
OpenAlexW4361001954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.