Evidence map›Paper›PMID 37056205›Full record

ReviewJournal of Zhejiang University. Science. B2023

Promising roles of non-exosomal and exosomal non-coding RNAs in the regulatory mechanism and as diagnostic biomarkers in myocardial infarction.

Jingru Li, Haocheng Ma, Xinyu Wu, Guihu Sun, Ping Yang, Yunzhu Peng, Qixian Wang, Luqiao Wang

Open access · greenAbstract readReview
In one paragraph

Review in Journal of Zhejiang University. Science. B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jingru LiDepartment of Cardiology, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
Haocheng MaDepartment of Cardiology, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
Xinyu WuDepartment of Cardiology, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
Guihu SunDepartment of Cardiology, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
Ping YangDepartment of Cardiology, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
Yunzhu PengDepartment of Cardiology, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
Qixian WangDepartment of Cardiology, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
Luqiao WangDepartment of Cardiology, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China. wlq8360@163.com.
Kunming Medical University · CN

Funding

the 100 Young and Middle-aged Academic and Technical Backbones of Kunming Medical University 60118260106the Clinical Medical Center for Cardiovascular and Cerebrovascular Disease of Yunnan Province ZX2019-03-01the Graduate Student Innovation Fund of Kunming Medical University 2022S035the National Natural Science Foundation of China 81860073, 81760074 and 82160439the Young Talents of Yunnan Thousand Talents Plan YNQR-QNRC-2019-006 and RLQN20200002the Yunnan Health Training Project of High-Level Talents H-2018032the Yunnan Provincial Department of Science and Technology 202001AT070039
6 · The paper itself

Abstract

Non-exosomal non-coding RNAs (non-exo-ncRNAs) and exosomal ncRNAs (exo-ncRNAs) have been associated with the pathological development of myocardial infarction (MI). Accordingly, this analytical review provides an overview of current MI studies on the role of plasma non-exo/exo-ncRNAs. We summarize the features and crucial roles of ncRNAs and reveal their novel biological correlations via bioinformatics analysis. The following contributions are made: (1) we comprehensively describe the expression profile, competing endogenous RNA (ceRNA) network, and "pre-necrotic" biomarkers of non-exo/exo-ncRNAs for MI; (2) functional enrichment analysis indicates that the target genes of ncRNAs are enriched in the regulation of apoptotic signaling pathway and cellular response to chemical stress, etc.; (3) we propose an updated and comprehensive view on the mechanisms, pathophysiology, and biomarker roles of non-exo/exo-ncRNAs in MI, thereby providing a theoretical basis for the clinical management of MI.

Indexed as

MicroRNAsMyocardial InfarctionBiomarkersComputational BiologyHumansRNARNA, UntranslatedBiomarkersMicroRNAsRNARNA, UntranslatedCircular RNA (circRNA)Exosomal ncRNAExosomeLong non-coding RNA (lncRNA)MicroRNA (miRNA)Myocardial Infarction (MI)Non-exosomal non-coding RNA (ncRNA)

Identifiers

PMID37056205
PMCPMC10106394
OpenAlexW4365479633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.