Evidence map›Paper›PMID 37056159›Full record

ArticleKorean journal of radiology2023

Assessment of Meningeal Lymphatics in the Parasagittal Dural Space: A Prospective Feasibility Study Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging.

Bio Joo, Mina Park, Sung Jun Ahn, Sang Hyun Suh

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bio JooDepartment of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0001-7460-1421
Mina ParkDepartment of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. to.minapark@yuhs.ac.ORCID 0000-0002-2005-7560
Sung Jun AhnDepartment of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0003-0075-2432
Sang Hyun SuhDepartment of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-7098-4901
Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMeningeal lymphatic vessels are predominantly located in the parasagittal dural space (PSD); these vessels drain interstitial fluids out of the brain and contribute to the glymphatic system. We aimed to investigate the ability of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in assessing the dynamic changes in the meningeal lymphatic vessels in PSD. MATERIALS AND

methodsEighteen participants (26-71 years; male:female, 10:8), without neurological or psychiatric diseases, were prospectively enrolled and underwent DCE-MRI. Three regions of interests (ROIs) were placed on the PSD, superior sagittal sinus (SSS), and cortical vein. Early and delayed enhancement patterns and six kinetic curve-derived parameters were obtained and compared between the three ROIs. Moreover, the participants were grouped into the young (< 65 years; n = 9) or older (≥ 65 years; n = 9) groups. Enhancement patterns and kinetic curve-derived parameters in the PSD were compared between the two groups.

resultsThe PSD showed different enhancement patterns than the SSS and cortical veins (

conclusionThis study shows that the dynamic changes of meningeal lymphatic vessels in PSD can be assessed with DCE-MRI, and the results are different from those of the venous structures. Our finding that delayed wash-out was more pronounced in the PSD of older participants suggests that aging may disturb the meningeal lymphatic drainage.

Indexed as

Dura MaterImage EnhancementLymphatic VesselsSuperior Sagittal SinusAdultAgedContrast MediaFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedContrast MediaAgingCentral nervous systemGlymphatic systemMagnetic resonance imagingMeningeal lymphatic system

Identifiers

PMID37056159
PMCPMC10157328
OpenAlexW4365421097

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.