Evidence map›Paper›PMID 37056069›Full record

ArticleThe Indian journal of medical research2022

Cost-effectiveness analysis of 'test and treat' policy for antiretroviral therapy among heterosexual HIV population in India.

Malkeet Singh, Aman Sharma, Pankaj Bahuguna, Gaurav Jyani, Shankar Prinja

Open access · diamondAbstract readComment
In one paragraph

Article in The Indian journal of medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Varied Immunological Response to Test and Treat with Antiretroviral Therapy: A Longitudinal Study with Mixed Model Analysis.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Malkeet SinghDepartment of Community Medicine & School of Public Health, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Aman SharmaDepartment of Internal Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Pankaj BahugunaDepartment of Community Medicine & School of Public Health, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Gaurav JyaniDepartment of Community Medicine & School of Public Health, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Shankar PrinjaDepartment of Community Medicine & School of Public Health, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background & objectives: The World Health Organisation recommended immediate initiation of antiretroviral therapy (ART) in all adult human immunodeficiency virus (HIV) patients regardless of their CD4 cell count. This study was undertaken to ascertain the cost-effectiveness of implementation of these guidelines in India. Methods: A Markov model was developed to assess the lifetime costs and health outcomes of three scenarios for initiation of ART treatment at varying CD4 cell count <350/mm Result: Test and treat intervention slowed down the progression of disease and averted 18,386 HIV-related deaths, over lifetime horizon. It also averted 16,105 new HIV infections and saved 343,172 QALYs as compared to the strategy of starting ART at CD4 cell count of 500/mm Interpretation & conclusions: Immediate ART (test and treat) is highly cost-effective strategy over the past criteria of delayed therapy in India. Cost-effectiveness of this policy is largely because of reduction in the transmission of HIV.

Indexed as

HIV InfectionsAdultAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountCost-Benefit AnalysisCost-Effectiveness AnalysisHealth Care CostsHeterosexualityHIVHumansIndiaPolicyQuality-Adjusted Life YearsAntiretroviral therapyCD4cost-effectiveness analyseseconomic evaluationHIVIndia –modellingtest and treat

Identifiers

PMID37056069
PMCPMC10278921
OpenAlexW4364322959

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.