ArticleJournal of nanobiotechnology2023
In situ forming ROS-scavenging hybrid hydrogel loaded with polydopamine-modified fullerene nanocomposites for promoting skin wound healing.
Article in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 94 citations in OpenAlex.
- Article
- Advancements in Functional Polymeric Scaffolds for Scar-Free Skin Regeneration.Polymer science & technology (Washington, D.C.) · 2026Review
- Photothermal-Activable Artificial Macrophage With Amplified Systemic Antibacterial Responses to Combat Primary and Secondary Infection.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Recent Research Progress on Multifunctional Biomimetic Polydopamine-Based Hydrogels for Wound Repair: A Review.Advanced healthcare materials · 2026Review
- Shattering the "golden armor": A natural supramolecular nanoplatform for optical virulence modulation and MRSA keratitis therapy.Materials today. Bio · 2026Article
- Spinal cord extracellular matrix hydrogel enhances organoid maturation and functional regeneration after spinal cord injury.Materials today. Bio · 2026Article
- Multifunctional scaffold based on TiMaterials today. Bio · 2026Article
- Cascade-Responsive MXene@Cu-MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Hydrogels for Bone Repair: Construction Strategies and Applications.Smart medicine · 2026Review
- Bakuchiol-loaded amphiphilic polymeric nanoparticles: enhancing stability and multifunctionality through encapsulation.Journal of biological engineering · 2026Article
- Recent Progress and Morphological Distribution of Polydopamine-Based Biomaterials and Their Applications.Gels (Basel, Switzerland) · 2026Review
- Human ES cell-derived MSC spheroids encapsulated in polydopamine nanoparticle-modified GelMA hydrogel enhance diabetic wound healing.Journal of nanobiotechnology · 2026Article
- Emerging stimuli-responsive hydrogels for enhancing chronic wound healing.RSC applied polymers · 2026Review
- Rectal In Situ Thermosensitive Gel Loaded with Agomelatine-Silver Nanoparticles: Formulation and Characterization.Gels (Basel, Switzerland) · 2026Article
- Chemically modified gelatin derivatives: synthetic strategies, physicochemical properties, biodegradation, drug delivery and biomedical applications.Frontiers in pharmacology · 2026Review
- Reinstating Niche Failure in Diabetic Cranial Defects via Chronotaxic Signal-Amplifying Fluidic Biomimetic Hydrogel.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- ROS-Triggered Microgels for Programmable Drug Release in Volumetric Muscle Loss Repair.Advanced healthcare materials · 2026Article
- Antimicrobial Hydrogel for Diabetic Wound Treatment.International journal of nanomedicine · 2026Review
- Dual-domain engineered exosome-based self-powered microneedle delivery platform for the treatment of infected wounds.Materials today. Bio · 2025Article
- Carbon nanomaterials: Exploring new frontiers in wound healing therapy.Bioengineering & translational medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExcessive oxidative stress at the wound sites always leads to a prolonged healing and even causes chronic inflammatory wounds. Therefore, antioxidative dressings with multiple features are desired to improve wound healing performance. Herein, we fabricated a ROS-scavenging hybrid hydrogel by incorporating mussel-inspired fullerene nanocomposites (C60@PDA) into gelatin methacryloyl (GelMA) hydrogel.
resultsThe developed C60@PDA/GelMA hydrogel showed a sustainable free radical scavenging ability, and eliminated ROS to protect cells against external oxidative stress damage. Besides, the hydrogel presented favorable cytocompatibility, hemocompatibility, and antibacterial ability in vitro. Furthermore, in a mouse full-thickness wound defect model, the in situ forming hybrid hydrogel accelerated wound closure by 38.5% and 42.9% on day 3 and day 7 over the control. Histological results demonstrated that hybrid hydrogels effectively enhanced wound healing on re-epithelialization, collagen deposition and angiogenesis.
conclusionCollectively, the C60@PDA/GelMA hydrogel could be a promising dressing for promoting cutaneous wound repair.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.