Evidence map›Paper›PMID 37055586›Full record

ArticleAbdominal radiology (New York)2023

Intra-examination agreement between multi-echo gradient echo and confounder-corrected chemical shift-encoded MR sequences for R2* estimation as a biomarker of liver iron content in patients with a wide range of T2*/R2* and proton density fat fraction values.

Guilherme Moura Cunha, Orpheus Kolokythas, Wenyu Chen, Halit Akcicek, Dave Hitt, Noah E Briller, Kathan Amin

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Article in Abdominal radiology (New York), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Guilherme Moura CunhaDepartment of Radiology, University of Washington, 1705 NE Pacific St., Box 357233, Seattle, WA, 98195, USA. gcunha@uw.edu.ORCID http://orcid.org/0000-0001-6403-5155
Orpheus KolokythasDepartment of Radiology, University of Washington, 1705 NE Pacific St., Box 357233, Seattle, WA, 98195, USA.
Wenyu ChenDepartment of Statistics, University of Washington, Seattle, WA, USA.
Halit AkcicekDepartment of Radiology, University of Washington, 1705 NE Pacific St., Box 357233, Seattle, WA, 98195, USA.
Dave HittPhilips Healthcare North America, Cleveland, OH, USA.
Noah E BrillerDepartment of Radiology, University of Washington, 1705 NE Pacific St., Box 357233, Seattle, WA, 98195, USA.
Kathan AminDepartment of Radiology, University of Washington, 1705 NE Pacific St., Box 357233, Seattle, WA, 98195, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the intra-examination agreement between multi-echo gradient echo (MEGE) and confounder-corrected chemical shift-encoded (CSE) sequences for liver T2*/R2* estimations in a wide range of T2*/R2* and proton density fat fraction (PDFF) values. Exploratorily, to search for the T2*/R2* value where the agreement line breaks and examine differences between regions of low and high agreement.

methodsConsecutive patients at risk for liver iron overload who underwent MEGE and CSE sequences within the same exam at 1.5 T were retrospectively selected. Regions of interest were drawn in the right and one in the left liver lobes on post-processed images for R2*(sec

results49 patients were included. Mean MEGE-R2* was 94.2 s

conclusionMEGE-R2* and CSE-R2* strongly agree, though at higher iron content, MEGE-R2* is consistently lower than CSE-R2*. In this preliminary dataset, a breaking point for agreement was found at R2* > 235. Lower agreement was observed in patients with moderate to severe liver steatosis.

Indexed as

IronProtonsBiomarkersHumansImage Interpretation, Computer-AssistedLiverMagnetic Resonance ImagingRetrospective StudiesBiomarkersIronProtonsIron quantificationLiverMagnetic resonance

Identifiers

PMID37055586

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