Evidence map›Paper›PMID 37055444›Full record

ArticleScientific reports2023

Association between the Cardiac Arrest Hospital Prognosis (CAHP) score and reason for death after successfully resuscitated cardiac arrest.

Marine Paul, Stéphane Legriel, Sarah Benghanem, Sofia Abbad, Alexis Ferré, Guillaume Lacave, Olivier Richard, Florence Dumas, Alain Cariou

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Marine PaulIntensive Care Unit, Centre Hospitalier de Versailles-Site André Mignot, 177 Rue de Versailles, 78150, Le Chesnay, France. mpaul@ght78sud.fr.ORCID 0000-0002-0717-9555
Stéphane LegrielIntensive Care Unit, Centre Hospitalier de Versailles-Site André Mignot, 177 Rue de Versailles, 78150, Le Chesnay, France.
Sarah BenghanemAfterROSC Study Group, Paris, France.
Sofia AbbadIntensive Care Unit, Centre Hospitalier de Versailles-Site André Mignot, 177 Rue de Versailles, 78150, Le Chesnay, France.
Alexis FerréIntensive Care Unit, Centre Hospitalier de Versailles-Site André Mignot, 177 Rue de Versailles, 78150, Le Chesnay, France.
Guillaume LacaveIntensive Care Unit, Centre Hospitalier de Versailles-Site André Mignot, 177 Rue de Versailles, 78150, Le Chesnay, France.
Olivier RichardSAMU 78, Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay Cedex, France.
Florence DumasAfterROSC Study Group, Paris, France.
Alain CariouAfterROSC Study Group, Paris, France.
Centre Hospitalier de Versailles · FRDélégation Paris 5 · FRFondation pour la Recherche Stratégique · FRHôpital Cochin · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Individualize treatment after cardiac arrest could potentiate future clinical trials selecting patients most likely to benefit from interventions. We assessed the Cardiac Arrest Hospital Prognosis (CAHP) score for predicting reason for death to improve patient selection. Consecutive patients in two cardiac arrest databases were studied between 2007 and 2017. Reasons for death were categorised as refractory post-resuscitation shock (RPRS), hypoxic-ischaemic brain injury (HIBI) and other. We computed the CAHP score, which relies on age, location at OHCA, initial cardiac rhythm, no-flow and low-flow times, arterial pH, and epinephrine dose. We performed survival analyses using the Kaplan-Meier failure function and competing-risks regression. Of 1543 included patients, 987 (64%) died in the ICU, 447 (45%) from HIBI, 291 (30%) from RPRS, and 247 (25%) from other reasons. The proportion of deaths from RPRS increased with CAHP score deciles; the sub-hazard ratio for the tenth decile was 30.8 (9.8-96.5; p < 0.0001). The sub-hazard ratio of the CAHP score for predicting death from HIBI was below 5. Higher CAHP score values were associated with a higher proportion of deaths due to RPRS. This score may help to constitute uniform patient populations likely to benefit from interventions assessed in future randomised controlled trials.

Indexed as

Cardiopulmonary ResuscitationOut-of-Hospital Cardiac ArrestEpinephrineHospitalsHumansPrognosisEpinephrine

Identifiers

PMID37055444
PMCPMC10102274
OpenAlexW4365452162

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.