Evidence map›Paper›PMID 37055210›Full record

ArticleBMJ open2023

Exercise during CHemotherapy for Ovarian cancer (ECHO) trial: design and implementation of a randomised controlled trial.

Sandra Hayes, Andreas Obermair, Linda Mileshkin, Alison Davis, Louisa G Gordon, Elizabeth Eakin, Monika Janda, Vanessa L Beesley, Elizabeth H Barnes, Rosalind Renee Spence and 14 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Exercise therapy in cancer prevention and treatment.Nature reviews. Clinical oncology · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 9 institutions in 5 countries.

Sandra HayesSchool of Health Sciences and Social Work, Menzies Health Institute Queensland, Griffith University, Brisbane, Queensland, Australia sandi.hayes@griffith.edu.au.ORCID 0000-0002-7005-5184
Andreas ObermairQueensland Centre for Gynaecological Cancer Research, University of Queensland, Brisbane, Queensland, Australia.
Linda MileshkinPeter MacCallum Cancer Centre, Victoria, Australia.
Alison DavisDepartment of Medical Oncology, The Canberra Hospital and ANU Medical School, Australian National University, Canberra, Australian Capital Territory, Australia.
Louisa G GordonQIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.ORCID 0000-0002-3159-4249
Elizabeth EakinSchool of Public Health, Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia.
Monika JandaCentre for Health Services Research, Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0002-1728-8085
Vanessa L BeesleyPopulation Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Elizabeth H BarnesUniversity of Sydney, NHMRC Clinical Trials Centre, Camperdown, New South Wales, Australia.
Rosalind Renee SpenceSchool of Health Sciences and Social Work, Menzies Health Institute Queensland, Griffith University, Brisbane, Queensland, Australia.ORCID 0000-0002-5446-5562
Carolina SandlerSchool of Health Sciences and Social Work, Menzies Health Institute Queensland, Griffith University, Brisbane, Queensland, Australia.
Tamara JonesSchool of Health Sciences and Social Work, Menzies Health Institute Queensland, Griffith University, Brisbane, Queensland, Australia.
Dimitrios VagenasSchool of Public Health and Social Work, Queensland University of Technology, Brisbane, Queensland, Australia.
Penny WebbPopulation Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
John AndrewsUniversity of Sydney, NHMRC Clinical Trials Centre, Camperdown, New South Wales, Australia.
Alison BrandDepartment of Gynaecological Oncology, Westmead Hospital, Westmead, New South Waled and University of Sydney, Sydney, New South Wales, Australia.
Yeh Chen LeeUniversity of Sydney, NHMRC Clinical Trials Centre, Camperdown, New South Wales, Australia.
Michael FriedlanderPrince of Wales Clinical School, Faculty of Medicine and Health, University of New South Wales, Randwick, New South Wales, Australia.
Kate PumpaResearch Institute for Sport and Exercise, University of Canberra, Canberra, Australian Capital Territory, Australia.
Helene O'NeilleConsumer representatives, Brisbane, Queensland, Australia.
Merran WilliamsConsumer representatives, Brisbane, Queensland, Australia.
ECHO Collaborative
Martin StocklerUniversity of Sydney, NHMRC Clinical Trials Centre, Camperdown, New South Wales, Australia.ORCID 0000-0003-3793-8724
ECHO trial
The University of Sydney · AUGriffith University · AUThe University of Queensland · AUQIMR Berghofer Medical Research Institute · AUQueensland University of Technology · AUAustralian National University · AUPeter MacCallum Cancer Centre · AUUniversity of Canberra · AUUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEpidemiological evidence supports an association between higher levels of physical activity and improved cancer survival. Trial evidence is now needed to demonstrate the effect of exercise in a clinical setting. The METHODS AND ANALYSIS: Participants (target sample size: n=500) include women with newly diagnosed primary ovarian cancer, scheduled to receive first-line chemotherapy. Consenting participants are randomly allocated (1:1) to either the ETHICS AND DISSEMINATION: Ethics approval for the ECHO trial (2019/ETH08923) was granted by the Sydney Local Health District Ethics Review Committee (Royal Prince Alfred Zone) on 21 November 2014. Subsequent approvals were granted for an additional 11 sites across Queensland, New South Wales, Victoria and the Australian Capital Territory. Findings from the ECHO trial are planned to be disseminated via peer-reviewed publications and international exercise and oncology conferences. TRIAL REGISTRATION NUMBER: Australian New Zealand Clinical Trial Registry (ANZCTRN12614001311640; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=367123&isReview=true).

Indexed as

Ovarian NeoplasmsQuality of LifeAustraliaClinical Trials, Phase III as TopicExerciseExercise TherapyFemaleHumansRandomized Controlled Trials as TopicGYNAECOLOGYONCOLOGYPUBLIC HEALTH

Identifiers

PMID37055210
PMCPMC10106078
OpenAlexW4365445760

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.