Evidence map›Paper›PMID 37055096›Full record

ReviewImmunology and allergy clinics of North America2023

Clinically Relevant Biomarkers in Connective Tissue Disease-Associated Interstitial Lung Disease.

Janelle Vu Pugashetti, Dinesh Khanna, Ella A Kazerooni, Justin Oldham

Open access · greenAbstract readReview
In one paragraph

Review in Immunology and allergy clinics of North America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Janelle Vu PugashettiDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan. Electronic address: vupugash@med.umich.edu.
Dinesh KhannaScleroderma Program, Division of Rheumatology, Department of Internal Medicine, University of Michigan.
Ella A KazerooniDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan; Division of Cardiothoracic Radiology, Department of Radiology, University of Michigan.
Justin OldhamDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan; Department of Epidemiology, University of Michigan.
University of Michigan–Ann Arbor · US

Funding

PULMONARY CELLULAR AND MOLECULAR BIOLOGY TRAININGT32HL007749 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Robert Pickett Dickson · 1993 to 2026
$19.9M
Proteomic Profiling of Idiopathic Pulmonary Fibrosis Progression TrajectoryR01HL169166 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin M Oldham · 2023 to 2026
$2.7M
Prognostic Biomarker Development in Progressive Fibrosing Interstitial Lung DiseaseR01HL166290 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin M Oldham · 2024 to 2026
$2.2M
Elucidating the Genomic Determinants of Outcomes in Idiopathic Pulmonary FibrosisK23HL138190 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OLDHAM, JUSTIN M · 2017 to 2021
$914k
Derivation and validation of a clinical-molecular signature to predict fibrotic progression and treatment response in patients with autoimmune interstitial lung diseaseR56HL158935 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI OLDHAM, JUSTIN M · 2021 to 2021
$400k
Interrogation of the inflammasome to identify biomarkers of progressive interstitial lung diseaseR03HL157895 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI OLDHAM, JUSTIN M · 2021 to 2022
$157k
NHLBI NIH HHS K23 HL138190NHLBI NIH HHS R01 HL166290NHLBI NIH HHS R01 HL169166NHLBI NIH HHS R03 HL157895NHLBI NIH HHS R56 HL158935NHLBI NIH HHS T32 HL007749
6 · The paper itself

Abstract

Interstitial lung disease (ILD) complicates connective tissue disease (CTD) with variable incidence and is a leading cause of death in these patients. To improve CTD-ILD outcomes, early recognition and management of ILD is critical. Blood-based and radiologic biomarkers that assist in the diagnosis CTD-ILD have long been studied. Recent studies, including -omic investigations, have also begun to identify biomarkers that may help prognosticate such patients. This review provides an overview of clinically relevant biomarkers in patients with CTD-ILD, highlighting recent advances to assist in the diagnosis and prognostication of CTD-ILD.

Indexed as

Connective Tissue DiseasesLung Diseases, InterstitialBiomarkersHumansTomography, X-Ray ComputedBiomarkersBiomarkersComputed tomographyConnective tissue diseaseInterstitial lung disease

Identifiers

PMID37055096
PMCPMC10584384
OpenAlexW4323051563

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.