Evidence map›Paper›PMID 37054885›Full record

ArticleThe American journal of clinical nutrition2023

Development and validation of new predictive equations for the resting metabolic rate of older adults aged ≥65 y.

Judi Porter, Leigh C Ward, Kay Nguo, Zoe Davidson, Simone Gibson, Ross Prentice, Marian L Neuhouser, Helen Truby

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Article in The American journal of clinical nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

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0cells of the map it votes in
8citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Judi PorterInstitute of Physical Activity and Nutrition, School of Exercise and Nutrition Science, Deakin University, Burwood, Melbourne, Victoria, Australia. Electronic address: judi.porter@deakin.edu.au.
Leigh C WardChemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia.
Kay NguoDepartment of Nutrition, Dietetics and Food, Monash University, Notting Hill, Melbourne, Victoria, Australia.
Zoe DavidsonDepartment of Nutrition, Dietetics and Food, Monash University, Notting Hill, Melbourne, Victoria, Australia.
Simone GibsonDepartment of Nutrition, Dietetics and Food, Monash University, Notting Hill, Melbourne, Victoria, Australia.
Ross PrenticeDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Marian L NeuhouserFred Hutchinson Cancer Research Center and School of Public Health and Community Medicine, University of Washington, Seattle, Washington, USA.
Helen TrubySchool of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, Queensland, Australia.

Funding

Nutrition and Physical Activity Assessment Study (NPAAS)R01CA119171 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Marian L Neuhouser · 2006 to 2026
$14.3M
NCI NIH HHS R01 CA119171NHLBI NIH HHS HHSN268201600001CNHLBI NIH HHS HHSN268201600003CNHLBI NIH HHS HHSN268201600004CNHLBI NIH HHS HHSN268201600018C
6 · The paper itself

Abstract

backgroundThe aging process alters the resting metabolic rate (RMR), but it still accounts for 50%-70% of the total energy needs. The rising proportion of older adults, especially those over 80 y of age, underpins the need for a simple, rapid method to estimate the energy needs of older adults.

objectivesThis research aimed to generate and validate new RMR equations specifically for older adults and to report their performance and accuracy.

methodsData were sourced to form an international dataset of adults aged ≥65 y (n = 1686, 38.5% male) where RMR was measured using the reference method of indirect calorimetry. Multiple regression was used to predict RMR from age (y), sex, weight (kg), and height (cm). Double cross-validation in a randomized, sex-stratified, age-matched 50:50 split and leave one out cross-validation were performed. The newly generated prediction equations were compared with the existing commonly used equations.

resultsThe new prediction equation for males and females aged ≥65 y had an overall improved performance, albeit marginally, when compared with the existing equations. It is described as follows: RMR (kJ/d) = 31.524 × W (kg) + 25.851 × H (cm) - 24.432 × Age (y) + 486.268 × Sex (M = 1, F = 0) + 530.557. Equations stratified by age (65-79.9 y and >80 y) and sex are also provided. The newly created equation estimates RMR within a population mean prediction bias of ∼50 kJ/d (∼1%) for those aged ≥65 y. Accuracy was reduced in adults aged ≥80 y (∼100 kJ/d, ∼2%) but was still within the clinically acceptable range for both males and females. Limits of agreement indicated a poorer performance at an individual level with 1.96-SD limits of approximately ±25%.

conclusionsThe new equations, using simple measures of weight, height, and age, improved the accuracy in the prediction of RMR in populations in clinical practice. However, no equation performs optimally at the individual level.

Indexed as

Basal MetabolismAgedBody Mass IndexBody WeightCalorimetry, IndirectFemaleHumansMalePredictive Value of Testsanthropometric measuresolder adultspredictionresting metabolic rateRMR

Identifiers

PMID37054885
PMCPMC10447471

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.