Evidence map›Paper›PMID 37054671›Full record

ReviewCell host & microbe2023

Cross-feeding in the gut microbiome: Ecology and mechanisms.

Elizabeth J Culp, Andrew L Goodman

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell host & microbe, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 301 papers.

0numbers the graph read from it
0cells of the map it votes in
301citing papers in PubMed
56.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

301 citing papers in PubMed, 363 citations in OpenAlex.

  1. Trial
  2. Bridging the gap:Gut microbes · 2026
    Review
  3. Review
  4. Article
  5. High dietary BGut microbes · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Engineering an asymmetric cross-feeding consortium inSynthetic and systems biotechnology · 2026
    Article
  18. The phenotypic landscape of the model firmicuteProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  19. Article
  20. Review

241 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Elizabeth J CulpDepartment of Microbial Pathogenesis and Microbial Sciences Institute, Yale University School of Medicine, New Haven, CT, USA.
Andrew L GoodmanDepartment of Microbial Pathogenesis and Microbial Sciences Institute, Yale University School of Medicine, New Haven, CT, USA. Electronic address: andrew.goodman@yale.edu.
Yale University · US

Funding

Causes and consequences of interpersonal microbial variationR35GM118159 · NIGMS · YALE UNIVERSITY · PI Andrew L Goodman · 2016 to 2026
$5.6M
Diet transformation by the microbiome and its impact on bacterial infectionR01DK133798 · NIDDK · YALE UNIVERSITY · PI Jorge E Galan, Andrew L Goodman · 2022 to 2026
$4.1M
Understanding the contributions of microbiome-encoded drug metabolizing enzymesR01AT010014 · NCCIH · YALE UNIVERSITY · PI GOODMAN, ANDREW L · 2019 to 2023
$2.1M
NCCIH NIH HHS R01 AT010014NIDDK NIH HHS R01 DK133798NIGMS NIH HHS R35 GM118159
6 · The paper itself

Abstract

Microbial communities are shaped by positive and negative interactions ranging from competition to mutualism. In the context of the mammalian gut and its microbial inhabitants, the integrated output of the community has important impacts on host health. Cross-feeding, the sharing of metabolites between different microbes, has emergent roles in establishing communities of gut commensals that are stable, resistant to invasion, and resilient to external perturbation. In this review, we first explore the ecological and evolutionary implications of cross-feeding as a cooperative interaction. We then survey mechanisms of cross-feeding across trophic levels, from primary fermenters to H

Indexed as

Gastrointestinal MicrobiomeMicrobiotaAnimalsBiological EvolutionHost Microbial InteractionsMammalsSymbiosis

Identifiers

PMID37054671
PMCPMC10125260
OpenAlexW4365136893

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.