Evidence map›Paper›PMID 37053380›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2023

Synthetic seismocardiogram generation using a transformer-based neural network.

Mohammad Nikbakht, Asim H Gazi, Jonathan Zia, Sungtae An, David J Lin, Omer T Inan, Rishikesan Kamaleswaran

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Mohammad NikbakhtDepartment of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.ORCID 0000-0002-5124-684X
Asim H GaziDepartment of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.ORCID 0000-0003-4698-2823
Jonathan ZiaDepartment of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.
Sungtae AnDepartment of Interactive Computing, Georgia Institute of Technology, Atlanta, Georgia, USA.
David J LinDepartment of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.
Omer T InanDepartment of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.
Rishikesan KamaleswaranDepartment of Biomedical Informatics, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0001-8366-4811

Funding

Sepsis Physiomarkers for Appropriate Risk Knowledge of monitored patients in the ICU (SPARK-ICU)R01GM139967 · NIGMS · EMORY UNIVERSITY · PI KAMALESWARAN, RISHIKESAN · 2021 to 2025
$2.8M
NIGMS NIH HHS R01 GM139967NIH HHS R01GM139967
6 · The paper itself

Abstract

objectiveTo design and validate a novel deep generative model for seismocardiogram (SCG) dataset augmentation. SCG is a noninvasively acquired cardiomechanical signal used in a wide range of cardivascular monitoring tasks; however, these approaches are limited due to the scarcity of SCG data.

methodsA deep generative model based on transformer neural networks is proposed to enable SCG dataset augmentation with control over features such as aortic opening (AO), aortic closing (AC), and participant-specific morphology. We compared the generated SCG beats to real human beats using various distribution distance metrics, notably Sliced-Wasserstein Distance (SWD). The benefits of dataset augmentation using the proposed model for other machine learning tasks were also explored.

resultsExperimental results showed smaller distribution distances for all metrics between the synthetically generated set of SCG and a test set of human SCG, compared to distances from an animal dataset (1.14× SWD), Gaussian noise (2.5× SWD), or other comparison sets of data. The input and output features also showed minimal error (95% limits of agreement for pre-ejection period [PEP] and left ventricular ejection time [LVET] timings are 0.03 ± 3.81 ms and -0.28 ± 6.08 ms, respectively). Experimental results for data augmentation for a PEP estimation task showed 3.3% accuracy improvement on an average for every 10% augmentation (ratio of synthetic data to real data).

conclusionThe model is thus able to generate physiologically diverse, realistic SCG signals with precise control over AO and AC features. This will uniquely enable dataset augmentation for SCG processing and machine learning to overcome data scarcity.

Indexed as

Machine LearningNeural Networks, ComputerEndoscopyHeart RateHumanscardiovascularmachine learningseismocardiogramtransformer neural networks

Identifiers

PMID37053380
PMCPMC10280352

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.