Evidence map›Paper›PMID 37053178›Full record

ArticlePloS one2023

Physical activity and cognitive function: A comparison of rural and urban breast cancer survivors.

Lindsey L Page, Christina J Kahn, Joan Severson, Arthur F Kramer, Edward McAuley, Diane K Ehlers

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Lymph node dissection, pain, and psychological factors: association with sleep quality during the perioperative period in oral cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Lindsey L PageDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, United States of America.ORCID 0000-0001-9439-8520
Christina J KahnDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, United States of America.
Joan SeversonDigital Artefacts, LLC, Iowa City, IA, United States of America.
Arthur F KramerNortheastern University, Boston, MA, United States of America.
Edward McAuleyUniversity of Illinois at Urbana-Champaign, Urbana, IL, United States of America.
Diane K EhlersDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, United States of America.
University of Nebraska Medical Center · USDigital Artefacts (United States) · USMayo Clinic in Arizona · USNortheastern University · USUniversity of Illinois Urbana-Champaign · US

Funding

EPA EP-D-16-021NCI NIH HHS L30 CA209645
6 · The paper itself

Abstract

purposeIncreasing evidence suggests rural breast cancer survivors (BCS) may experience greater burden in symptoms known to be associated with cancer-associated cognitive decline (CACD). Yet, little is known about CACD in rural BCS. This study (1) examined differences in cognitive function, moderate-to-vigorous physical activity (MVPA), and other CACD correlates and (2) tested the effects of MVPA on cognitive function in rural versus urban BCS.

methodsRural and urban BCS (N = 80), matched on age, education, and time since diagnosis from a larger study, completed cognitive tasks assessing processing speed (Trails-B, Mazes, Task-Switch) and working memory (spatial working memory) and questionnaires assessing subjective memory impairment (SMI), MVPA, and CACD correlates (i.e., sleep quality, fatigue, anxiety/depression). Some participants (n = 62) wore an accelerometer to objectively estimate MVPA. Multiple linear regression and multivariate analysis of covariance were used to test study aims.

resultsRural BCS (n = 40, M = 61.1±8.4 years-old) performed significantly slower on Trails-B (p<0.01) compared with urban BCS (n = 40, M = 61.0±8.2 years-old) and engaged in less objectively-estimated daily MVPA (mean difference = 13.83±4.73 minutes; p = 0.01). No significant differences in SMI, self-reported MVPA, or CACD correlates were observed (all p>0.28). Regression models did not reveal a significant interaction between MVPA and cognitive performance (all p>0.1); however, estimated marginal means models indicated that the effect of MVPA on processing speed was evident only among rural BCS (Trails-B, p = 0.04; Mazes, p = 0.03).

conclusionsFindings suggest rural BCS may suffer greater CACD and engage in less MVPA. Additional research is warranted to further examine CACD and more effectively promote MVPA in rural BCS.

Indexed as

Breast NeoplasmsCancer SurvivorsAgedCognitionExerciseFemaleHumansMemory DisordersMiddle AgedSurvivors

Identifiers

PMID37053178
PMCPMC10101459
OpenAlexW4365443136

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.