Evidence map›Paper›PMID 37053164›Full record

ReviewPLoS pathogens2023

Environmental reservoirs of the drug-resistant pathogenic yeast Candida auris.

Ayorinde B Akinbobola, Ryan Kean, Syed Manzoor Ahmed Hanifi, Richard S Quilliam

Open access · goldAbstract readReview
In one paragraph

Review in PLoS pathogens, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 65 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Microbiology spectrum · 2026
    Article
  10. UnderstandingJournal of medical microbiology · 2026
    Review
  11. Review
  12. Article
  13. Transboundary and emerging diseases · 2026
    Article
  14. Article
  15. Microbiology spectrum · 2025
    Article
  16. Article
  17. Article
  18. Discrimination of Clinical and Food-DerivedPathogens (Basel, Switzerland) · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Ayorinde B AkinbobolaBiological and Environmental Sciences, Faculty of Natural Sciences, University of Stirling, Stirling, United Kingdom.ORCID 0000-0002-6617-2791
Ryan KeanDepartment of Biological and Biomedical Sciences, School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, United Kingdom.
Syed Manzoor Ahmed HanifiInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Health System and Population Studies Division, Shaheed Tajuddin Ahmed Sarani, Mohakhali, Dhaka, Bangladesh.
Richard S QuilliamBiological and Environmental Sciences, Faculty of Natural Sciences, University of Stirling, Stirling, United Kingdom.
University of Stirling · GBGlasgow Caledonian University · GBInternational Centre for Diarrhoeal Disease Research · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candia auris is an emerging human pathogenic yeast; yet, despite phenotypic attributes and genomic evidence suggesting that it probably emerged from a natural reservoir, we know nothing about the environmental phase of its life cycle and the transmission pathways associated with it. The thermotolerant characteristics of C. auris have been hypothesised to be an environmental adaptation to increasing temperatures due to global warming (which may have facilitated its ability to tolerate the mammalian thermal barrier that is considered a protective strategy for humans against colonisation by environmental fungi with pathogenic potential). Thus, C. auris may be the first human pathogenic fungus to have emerged as a result of climate change. In addition, the release of antifungal chemicals, such as azoles, into the environment (from both pharmaceutical and agricultural sources) is likely to be responsible for the environmental enrichment of resistant strains of C. auris; however, the survival and dissemination of C. auris in the natural environment is poorly understood. In this paper, we critically review the possible pathways through which C. auris can be introduced into the environment and evaluate the environmental characteristics that can influence its persistence and transmission in natural environments. Identifying potential environmental niches and reservoirs of C. auris and understanding its emergence against a backdrop of climate change and environmental pollution will be crucial for the development of effective epidemiological and environmental management responses.

Indexed as

CandidaCandida aurisAnimalsAntifungal AgentsClimate ChangeHumansMammalsMicrobial Sensitivity TestsAntifungal Agents

Identifiers

PMID37053164
PMCPMC10101498
OpenAlexW4365442770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.