Evidence map›Paper›PMID 37052814›Full record

ArticlePain and therapy2023

Long-Term Analgesic Efficacy of Neurolytic Splanchnic Nerve Block via the Transintervertebral Disc Approach to Retrocrural Space: A Multicenter Retrospective Study.

Ryota Yanaizumi, Yusuke Nagamine, Shinsuke Harada, Tomoko Kuramochi, Shuhei Ota, Yoichiro Abe, Masayuki Nakagawa, Kenya Kamijima, Maya Hayashi, Toshiharu Tazawa and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pain and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Splanchnic neurolysis for severe cancer pain caused by abdominal paraaortic lymph node metastasis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Ryota YanaizumiDepartment of Anesthesiology, Yokohama City University Medical Center, Yokohama, Japan.
Yusuke NagamineDepartment of Anesthesiology and Critical Care Medicine, Yokohama City University Hospital, 3-9 Fukuura, Kanazawa-Ku, Yokohama, Kanagawa, 236-0004, Japan. ynagamin@yokohama-cu.ac.jp.ORCID http://orcid.org/0000-0002-0443-5007
Shinsuke HaradaYu Home Care Clinic Asahi, Yokohama, Japan.
Tomoko KuramochiDepartment of Palliative Care, Yokohama Municipal Citizen's Hospital, Yokohama, Japan.
Shuhei OtaDepartment of Palliative Medicine, Kanagawa Cancer Center, Kanagawa, Japan.
Yoichiro AbeDepartment of Pain Clinic, NTT Medical Center Tokyo, Tokyo, Japan.
Masayuki NakagawaDepartment of Pain Clinic, NTT Medical Center Tokyo, Tokyo, Japan.
Kenya KamijimaDepartment of Pain Clinic, NTT Medical Center Tokyo, Tokyo, Japan.
Maya HayashiDepartment of Pain Clinic, NTT Medical Center Tokyo, Tokyo, Japan.
Toshiharu TazawaDepartment of Anesthesiology, Saint Marianna University School of Medicine, Kawasaki, Japan.
Kenichi OgawaKugenuma Palliative Care Internal Medicine, Fujisawa, Japan.
Takahisa GotoDepartment of Anesthesiology and Critical Care Medicine, Yokohama City University Hospital, 3-9 Fukuura, Kanazawa-Ku, Yokohama, Kanagawa, 236-0004, Japan.
NTT Medical Center · JPYokohama City University Hospital · JPKanagawa Prefectural Hospital Organization · JPMiwa Internal Medicine Clinic · JPSt. Marianna University School of Medicine · JPYokohama City University Medical Center · JPYokohama Municipal Citizen's Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe celiac plexus block is effective for treating intractable cancer pain and has been the focus of many studies. At our affiliated institution, fluoroscopy-guided splanchnic nerve block with a single needle via the transintervertebral disc approach was the first choice of treatment. The short-term efficacy of this technique has been reported, but the long-term efficacy is not clear. In the present study, we investigated the long-term analgesic efficacy of this technique.

methodsThis multicenter, retrospective, observational study reviewed the medical records of patients who underwent neurolytic splanchnic nerve block (NSNB) via the transintervertebral disc approach for intractable cancer pain at five tertiary hospitals in Japan from April 2005 to October 2020. The primary outcome was the long-term analgesic efficacy of a one-time NSNB via the transintervertebral disc approach.

resultsIn total, 76 patients were included in the analysis. The median lowest numerical rating scale (NRS) score was 1 within 14 days. At 1, 2, 3, and 6 months after the nerve block, the median NRS score was also ≤ 2, while the median equivalent oral morphine dose did not show any clinically noticeable increase at those times.

conclusionThe long-term analgesic efficacy of NSNB via the transintervertebral disc approach in patients with intractable cancer pain has been demonstrated.

Indexed as

Cancer painCeliac plexusInterventionalIntervertebral discNerve blockRadiologySplanchnic nerves

Identifiers

PMID37052814
PMCPMC10199966
OpenAlexW4365443613

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.