ArticleInsights into imaging2023
Radiomics model to classify mammary masses using breast DCE-MRI compared to the BI-RADS classification performance.
Article in Insights into imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Diagnosing breast masses in BI-RADS 4: construction and interpretation of an intralesional and perilesional radiomics nomogram based on digital breast tomosynthesis.BMC medical imaging · 2026Article
- Breast tumor segmentation and morphological feature-based classification in ultrasound using a two-stage U-net and SVM.Frontiers in bioengineering and biotechnology · 2026Article
- Radiomics-based Machine Learning Models for Classifying Breast Cancer on Dynamic-Contrast Enhanced MRI through Multi-Observer AnalysisCurrent medical imaging · 2026Article
- Development and validation of an integrated model combining deep learning, radiomics, and clinical and breast ultrasound features for Breast Imaging Reporting and Data System 4A lesion malignancy classification.Quantitative imaging in medicine and surgery · 2025Article
- Deep Learning-Based DCE-MRI Automatic Segmentation in Predicting Lesion Nature in BI-RADS Category 4.Journal of imaging informatics in medicine · 2025Article
- The Role of Synthetic MRI and Radiomics in Breast Cancer: A Review.Advanced biomedical research · 2025Review
- Artificial intelligence integrates multi-omics data for precision stratification and drug resistance prediction in breast cancer.Frontiers in oncology · 2025Review
- Development and validation of a nomogram for differentiating granulomatous lobular mastitis from ductal carcinoma in situ.Frontiers in oncology · 2025Article
- An updated overview of radiomics-based artificial intelligence (AI) methods in breast cancer screening and diagnosis.Radiological physics and technology · 2024Review
- Are we ready to stratify BI-RADS 4 MRI lesions?Radiologia brasileiraArticle
- New developments in the BI-RADS for MRI.Radiologia brasileiraArticle
- Quantitative DCE Dynamics on Transformed MR Imaging Discriminates Clinically Significant Prostate Cancer.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent advanced in radiomics analysis could help to identify breast cancer among benign mammary masses. The aim was to create a radiomics signature using breast DCE-MRI extracted features to classify tumors and to compare the performances with the BI-RADS classification. MATERIAL AND
methodsFrom September 2017 to December 2019 images, exams and records from consecutive patients with mammary masses on breast DCE-MRI and available histology from one center were retrospectively reviewed (79 patients, 97 masses). Exclusion criterion was malignant uncertainty. The tumors were split in a train-set (70%) and a test-set (30%). From 14 kinetics maps, 89 radiomics features were extracted, for a total of 1246 features per tumor. Feature selection was made using Boruta algorithm, to train a random forest algorithm on the train-set. BI-RADS classification was recorded from two radiologists.
resultsSeventy-seven patients were analyzed with 94 tumors, (71 malignant, 23 benign). Over 1246 features, 17 were selected from eight kinetic maps. On the test-set, the model reaches an AUC = 0.94 95 CI [0.85-1.00] and a specificity of 33% 95 CI [10-70]. There were 43/94 (46%) lesions BI-RADS4 (4a = 12/94 (13%); 4b = 9/94 (10%); and 4c = 22/94 (23%)). The BI-RADS score reached an AUC = 0.84 95 CI [0.73-0.95] and a specificity of 17% 95 CI [3-56]. There was no significant difference between the ROC curves for the model or the BI-RADS score (p = 0.19).
conclusionA radiomics signature from features extracted using breast DCE-MRI can reach an AUC of 0.94 on a test-set and could provide as good results as BI-RADS to classify mammary masses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.