Evidence map›Paper›PMID 37052373›Full record

ArticlemBio2023

Deficient Phagocytosis in Circulating Monocytes from Patients with COVID-19-Associated Mucormycosis.

Bishnu Prasad Sinha, Priyanka Mehta, Md Asmaul Hoque, Purbita Bandopadhyay, Ayandip Nandi, Ipsita Saha, Anita Nandi Mitra, Asish Mondal, Boudhayan Bhattacharjee, Georgios Chamilos and 3 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. COVID-19, mucormycosis, and the cow: Damned lies!Indian journal of medical microbiology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Bishnu Prasad Sinha *IICB-Translational Research Unit of Excellence, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Priyanka Mehta *INtegrative GENomics of HOst-PathogEn (INGEN-HOPE) Laboratory, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.
Md Asmaul HoqueIICB-Translational Research Unit of Excellence, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Purbita BandopadhyayIICB-Translational Research Unit of Excellence, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Ayandip NandiDepartment of Pathology, Medical College, Kolkata, India.
Ipsita SahaDepartment of Pathology, Medical College, Kolkata, India.
Anita Nandi MitraDepartment of Microbiology, Medical College, Kolkata, India.
Asish MondalDepartment of General Medicine, Medical College, Kolkata, India.
Boudhayan BhattacharjeeDepartment of Tropical Medicine, School of Tropical Medicine, Kolkata, India.
Georgios ChamilosInstitute of Molecular Biology & Biotechnology, Foundation for Research & Technology - Hellas (IMBB FoRTH), Heraklion, Greece.ORCID 0000-0002-7987-4055
Rajesh PandeyINtegrative GENomics of HOst-PathogEn (INGEN-HOPE) Laboratory, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.ORCID 0000-0002-4404-8327
Kaushik BasuDepartment of General Medicine, Medical College, Kolkata, India.
Dipyaman GangulyIICB-Translational Research Unit of Excellence, CSIR-Indian Institute of Chemical Biology, Kolkata, India.ORCID 0000-0002-7786-1795
Indian Institute of Chemical Biology · INKPC Medical College and Hospital · INInstitute of Genomics and Integrative Biology · INIndian Institute of Tropical Meteorology · INUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cases of rhino-orbital mucormycosis in patients suffering from severe coronavirus disease 2019 (COVID-19) were reported in different parts of the world, especially in India. However, specific immune mechanisms that are linked to susceptibility to COVID-19-associated mucormycosis (CAM) remain largely unexplored. We aimed to explore whether the differential regulation of circulating cytokines in CAM patients had any potential pathogenic links with myeloid phagocyte function and susceptibility to mucormycosis. A small cohort of Indian patients suffering from CAM (N = 9) as well as COVID-19 patients with no evidence of mucormycosis (N = 5) were recruited in the study. Venous blood was collected from the patients as well as from healthy volunteers (N = 8). Peripheral blood mononuclear cells and plasma were isolated. Plasma samples were used to measure a panel of 48 cytokines. CD14

Indexed as

COVID-19MucormycosisCytokinesHumansLeukocytes, MononuclearMonocytesPhagocytosisCytokinesCOVID-19cytokinesmonocytesmucormycosisphagocytosistranscriptome

Identifiers

PMID37052373
PMCPMC10294693
OpenAlexW4365443644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.