Evidence map›Paper›PMID 37051645›Full record

ArticleJournal of breast cancer2023

A Preliminary Experience of Endoscopic Total Mastectomy With Immediate Free Abdominal-Based Perforator Flap Reconstruction Using Minimal Incisions, and Literature Review.

Sabrina Ngaserin, Allen Wei-Jiat Wong, Faith Qi-Hui Leong, Jia-Jun Feng, Yee Onn Kok, Benita Kiat-Tee Tan

Open access · goldAbstract read
In one paragraph

Article in Journal of breast cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sabrina NgaserinBreast Service, Department of Surgery, Sengkang General Hospital, Singapore.ORCID https://orcid.org/0000-0002-4319-3389
Allen Wei-Jiat WongPlastic, Reconstructive & Aesthetic Surgery Service, Department of Surgery, Sengkang General Hospital, Singapore.ORCID https://orcid.org/0000-0001-7924-5155
Faith Qi-Hui LeongBreast Service, Department of Surgery, Sengkang General Hospital, Singapore.ORCID https://orcid.org/0000-0001-5657-7333
Jia-Jun FengPlastic, Reconstructive & Aesthetic Surgery Service, Department of Surgery, Sengkang General Hospital, Singapore.ORCID https://orcid.org/0000-0003-4424-0287
Yee Onn KokPlastic, Reconstructive & Aesthetic Surgery Service, Department of Surgery, Sengkang General Hospital, Singapore.ORCID https://orcid.org/0000-0001-8917-440X
Benita Kiat-Tee TanBreast Service, Department of Surgery, Sengkang General Hospital, Singapore.ORCID https://orcid.org/0000-0002-8573-4606
Sengkang General Hospital · SGSingHealth Duke-NUS Academic Medical Centre · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEndoscopic total mastectomy (ETM) is predominantly performed with reconstruction using prostheses, lipofilling, omental flaps, latissimus dorsi flaps, or a combination of these techniques. Common approaches include minimal incisions, e.g., periareolar, inframammary, axillary, or mid-axillary line, which limit the technical ability to perform autologous flap insets and microvascular anastomoses, as such the ETM with free abdominal-based perforator flap reconstruction has not been robustly explored.

methodsWe studied female patients with breast cancer who underwent ETM and abdominal-based flap reconstruction. Clinical-radiological-pathological characteristics, surgery, complications, recurrence rates, and aesthetic outcomes were reviewed.

resultsTwelve patients underwent ETM with abdominal-based flap reconstruction. The mean age was 53.4 years (range 36-65). Of the patients, 33.3% were surgically treated for stage I, 58.4% for stage II, and 8.3% for stage III cancer. Mean tumor size was 35.4 mm (range 1-67). Mean specimen weight was 458.75 g (range 242-800). Of the patients, 92.3% successfully received endoscopic nipple-sparing mastectomy and 7.7% underwent intraoperative conversion to skin-sparing mastectomy after carcinoma was reported on frozen section of the nipple base. Mean operative time for ETM was 139 minutes (92-198), and the average ischemic time was 37.3 minutes (range 22-50). Fifty percent of patients underwent deep inferior epigastric perforator, 33.4% underwent MS-2 transverse rectus abdominis musculocutaneous (TRAM), 8.3% underwent MS-1 TRAM, and 8.3% underwent pedicled TRAM flap reconstruction. No cases required re-exploration, no flap failure occurred, margins were clear, and no skin or nipple-areolar complex ischemia/necrosis developed. In the aesthetic outcome evaluation, 16.7% were excellent, 75% good, 8.3% fair, and none were unsatisfactory. No recurrences were observed.

conclusionETM through a minimal-access inferior mammary or mid-axillary line approach, followed by immediate pedicled TRAM or free abdominal-based perforator flap reconstruction, can be a safe means of achieving an "aesthetically scarless" mastectomy and reconstruction through minimal incisions.

Indexed as

Breast NeoplasmsFree Tissue FlapMastectomy, SubcutaneousPerforator Flap

Identifiers

PMID37051645
PMCPMC10139846
OpenAlexW4328022455

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.