ArticleFrontiers in cardiovascular medicine2023
Brachial-ankle pulse wave velocity trajectories in a middle-aged population.
Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Morning cortisol as an indicator of arterial stiffness in patients with type 2 diabetes: prospective cohort study and Mendelian randomization study.Frontiers in endocrinology · 2025Article
- Early vascular aging determined by brachial-ankle pulse wave velocity and its impact on ischemic stroke outcome: a retrospective observational study.Scientific reports · 2024Observational
- The Value of Serial Measurement of Arterial Stiffness in Cardiovascular Disease.Reviews in cardiovascular medicine · 2024Review
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Authors and funding
7 authors.
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Abstract
Objective: The "trajectory" phenotype was observed in several cardiovascular risk factors with aging. We aim to identify multiple brachial-ankle Pulse Wave Velocity (baPWV) trajectory phenotypes and assess their determinants. Methods: Among 5,182 participants with baPWV measurements (2010-2016) at no less than three time points in Kailuan Study, we derived baPWV trajectory pattern using SAS Proc Traj program. We applied the lowest Bayesian information criterion to identify the best typing model, related the identified trajectory pattern to baseline and changes in characteristics. Results: Among 5.3 ± 1.7 years follow-up, four distinct baPWV trajectories were identified as low (1,961,37.8%), medium-low (1,846,35.6%), medium-high (1,024,19.8%), and high (351,6.8%) groups. In the stepwise models, mean arterial pressure and age were the main determinators of the trajectory patterns, with a Δpseudo-R Conclusions: The changes in baPWV overtime followed a "trajectory" pattern, mainly determined by mean arterial pressure and age.
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