Evidence map›Paper›PMID 37050904›Full record

ArticleFrontiers in pharmacology2023

Population pharmacokinetics and model-based dosing evaluation of bedaquiline in multidrug-resistant tuberculosis patients.

Ge Shao, Ziwei Bao, Lina Davies Forsman, Jakob Paues, Jim Werngren, Katarina Niward, Thomas Schön, Judith Bruchfeld, Jan-Willem Alffenaar, Yi Hu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Population pharmacokinetics of bedaquiline: a systematic review.European journal of clinical pharmacology · 2025
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Bedaquiline Delivery Innovations: A Review on Advancing MDR-TB Treatment Strategies.Recent advances in anti-infective drug discovery · 2025
    Review
  12. Therapeutic drug monitoring in tuberculosis.European journal of clinical pharmacology · 2024
    Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 3 countries.

Ge ShaoDepartment of Epidemiology, School of Public Health and Key Laboratory of Public Health Safety, Fudan University, Shanghai, China.
Ziwei BaoThe Fifth People's Hospital of Suzhou, Infectious Disease Hospital Affiliated to Soochow University, Suzhou, China.
Lina Davies ForsmanDepartment of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.
Jakob PauesDepartment of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Jim WerngrenDepartment of Microbiology, Public Health Agency of Sweden, Stockholm, Sweden.
Katarina NiwardDepartment of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Thomas SchönDepartment of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Judith BruchfeldDepartment of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.
Jan-Willem AlffenaarUniversity of Sydney, Faculty of Medicine and Health, School of Pharmacy, Sydney, NSW, Australia.
Yi HuDepartment of Epidemiology, School of Public Health and Key Laboratory of Public Health Safety, Fudan University, Shanghai, China.
Fudan University · CNLinköping University Hospital · SEKarolinska Institutet · SEKarolinska University Hospital · SELinköping University · SEPublic Health Agency of Sweden · SEThe Fifth People’s Hospital of Suzhou · CNThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bedaquilinedosage evaluationmultidrug-resistant tuberculosispopulation pharmacokinetic modelingtarget attainment

Identifiers

PMID37050904
PMCPMC10083270
OpenAlexW4360985257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.