Evidence map›Paper›PMID 37050750›Full record

ArticleSensors (Basel, Switzerland)2023

Clinical Study of Continuous Non-Invasive Blood Pressure Monitoring in Neonates.

Anoop Rao, Fatima Eskandar-Afshari, Ya'el Weiner, Elle Billman, Alexandra McMillin, Noa Sella, Thomas Roxlo, Junjun Liu, Weyland Leong, Eric Helfenbein and 11 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06994494 (Noninvasive Continuous BP Monitoring in Newborns Based on Pulsatile Signal Morphological Features Using NIRS), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06994494 recruitingnot on this mapstarted 2025, after this paper: background citation

Noninvasive Continuous BP Monitoring in Newborns Based on Pulsatile Signal Morphological Features Using NIRS

TypeobservationalSponsorMassachusetts General HospitalRan2025 to 2026Enrolled80ConditionsUnstable Blood Pressure, Hypotension
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Monitoring and evaluation of hypotension in the extremely preterm.Frontiers in cardiovascular medicine · 2024
    Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 1 country.

Anoop RaoDepartment of Pediatrics, Division of Neonatal and Developmental Medicine, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.ORCID 0000-0002-5767-7464
Fatima Eskandar-AfshariDivision of Neonatology, LAC+USC Medical Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Ya'el WeinerDepartment of Emergency Medicine, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.
Elle BillmanDepartment of Anesthesia, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.ORCID 0000-0003-2861-6336
Alexandra McMillinDepartment of Pediatrics, Division of Neonatal and Developmental Medicine, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Noa SellaDepartment of Pediatrics, Division of Neonatal and Developmental Medicine, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Thomas RoxloPyrAmes Inc., Cupertino, CA 95014, USA.
Junjun LiuPyrAmes Inc., Cupertino, CA 95014, USA.
Weyland LeongPyrAmes Inc., Cupertino, CA 95014, USA.
Eric HelfenbeinPhilips Healthcare, Sunnyvale, CA 94085, USA.
Alan WalendowskiPyrAmes Inc., Cupertino, CA 95014, USA.
Arthur MuirPyrAmes Inc., Cupertino, CA 95014, USA.
Alexandria JosephDepartment of Anesthesia, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Archana VermaDepartment of Anesthesia, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Chandra RamamoorthyDepartment of Anesthesia, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Anita HonkanenDepartment of Anesthesia, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.ORCID 0000-0003-3934-7186
Gabrielle GreenDepartment of Pediatrics, Division of Neonatal and Developmental Medicine, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Keith DrakePyrAmes Inc., Cupertino, CA 95014, USA.
Rathinaswamy B GovindanChildren's National Hospital, Washington, DC 20010, USA.
William RhineDepartment of Pediatrics, Division of Neonatal and Developmental Medicine, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.ORCID 0000-0003-0100-505X
Xina QuanPyrAmes Inc., Cupertino, CA 95014, USA.
Stanford University · USChildren's Hospital of Los Angeles · USChildren's National · USPhilips (United States) · USUniversity of Southern California · US

Funding

Continuous Non-Invasive Blood Pressure Monitor for NeonatesR43HD101175 · NICHD · PYRAMES, INC. · PI QUAN, XINA · 2020 to 2020
$225k
FDA HHS P50 FD006430NICHD NIH HHS R43 HD101175NIH HHS 1R43HD101175Stanford Medicine MCHRIUnited States Food and Drug Administration P50FD006430
6 · The paper itself

Abstract

The continuous monitoring of arterial blood pressure (BP) is vital for assessing and treating cardiovascular instability in a sick infant. Currently, invasive catheters are inserted into an artery to monitor critically-ill infants. Catheterization requires skill, is time consuming, prone to complications, and often painful. Herein, we report on the feasibility and accuracy of a non-invasive, wearable device that is easy to place and operate and continuously monitors BP without the need for external calibration. The device uses capacitive sensors to acquire pulse waveform measurements from the wrist and/or foot of preterm and term infants. Systolic, diastolic, and mean arterial pressures are inferred from the recorded pulse waveform data using algorithms trained using artificial neural network (ANN) techniques. The sensor-derived, continuous, non-invasive BP data were compared with corresponding invasive arterial line (IAL) data from 81 infants with a wide variety of pathologies to conclude that inferred BP values meet FDA-level accuracy requirements for these critically ill, yet normotensive term and preterm infants.

Indexed as

Blood Pressure DeterminationInfant, PrematureArterial PressureBlood PressureHumansInfantInfant, NewbornWristcNIBPhypertensionhypotensionneonateNICUnon-invasive blood pressure monitoring

Identifiers

PMID37050750
PMCPMC10098632
OpenAlexW4362578520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.