Evidence map›Paper›PMID 37050407›Full record

ArticlePolymers2023

Eudragit Films as Carriers of Lipoic Acid for Transcorneal Permeability.

Karina L Bierbrauer, Laura R Comini, Victoria Leonhard, Micaela A Escobar Manzanelli, Gabriela Castelli, Silvia Farfán, Roxana V Alasino, Dante M Beltramo

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Karina L BierbrauerCentro de Excelencia en Productos y Procesos de Córdoba, Gobierno de la Provincia de Córdoba, Pabellón CEPROCOR, Santa María de Punilla, Córdoba CP 5164, Argentina.
Laura R CominiCentro de Excelencia en Productos y Procesos de Córdoba, Gobierno de la Provincia de Córdoba, Pabellón CEPROCOR, Santa María de Punilla, Córdoba CP 5164, Argentina.
Victoria LeonhardCentro de Excelencia en Productos y Procesos de Córdoba, Gobierno de la Provincia de Córdoba, Pabellón CEPROCOR, Santa María de Punilla, Córdoba CP 5164, Argentina.
Micaela A Escobar ManzanelliCentro de Excelencia en Productos y Procesos de Córdoba, Gobierno de la Provincia de Córdoba, Pabellón CEPROCOR, Santa María de Punilla, Córdoba CP 5164, Argentina.
Gabriela CastelliCentro de Excelencia en Productos y Procesos de Córdoba, Gobierno de la Provincia de Córdoba, Pabellón CEPROCOR, Santa María de Punilla, Córdoba CP 5164, Argentina.
Silvia FarfánCentro de Excelencia en Productos y Procesos de Córdoba, Gobierno de la Provincia de Córdoba, Pabellón CEPROCOR, Santa María de Punilla, Córdoba CP 5164, Argentina.
Roxana V AlasinoCentro de Excelencia en Productos y Procesos de Córdoba, Gobierno de la Provincia de Córdoba, Pabellón CEPROCOR, Santa María de Punilla, Córdoba CP 5164, Argentina.
Dante M BeltramoCentro de Excelencia en Productos y Procesos de Córdoba, Gobierno de la Provincia de Córdoba, Pabellón CEPROCOR, Santa María de Punilla, Córdoba CP 5164, Argentina.
Centro Científico Tecnológico - Córdoba · ARCentro de Excelencia en Procesos y Productos de Córdoba · AR

Funding

CEPROCOR PBIO13
6 · The paper itself

Abstract

Diabetes mellitus (DM) is a highly prevalent disease affecting almost 10% of the world population; it is characterized by acute and chronic conditions. Diabetic patients have twenty-five times higher risk of going blind and developing cataracts early than the general population. Alpha-lipoic acid (LA) is a highly valuable natural antioxidant for the prevention and treatment of ophthalmic complications, such as diabetic keratopathy and retinopathy. However, its applicability is limited due to its low solubility in water; therefore, suitable systems are required for its formulation. In this work we developed an erodible insert based on Eudragit E100 (

Indexed as

corneal permeabilitydrug releaseEudragit E100 filmsLipoic Acidmechanical propertiesmucoadhesivity

Identifiers

PMID37050407
PMCPMC10097161
OpenAlexW4362619983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.