Evidence map›Paper›PMID 37050390›Full record

ArticlePolymers2023

Cloning, Expression, and Characterization of a Highly Stable Heparinase I from

Jia-Lu Pei, Wei Wei, Ding-Ran Wang, Cai-Yun Liu, Hua-Ping Zhou, Chen-Lu Xu, Ye-Wang Zhang

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jia-Lu PeiSchool of Pharmacy, Jiangsu University, Zhenjiang 212013, China.ORCID 0009-0009-1334-9512
Wei WeiZhongshiduqing Biotechnology Co., Ltd., Heze 274100, China.
Ding-Ran WangSchool of Pharmacy, Jiangsu University, Zhenjiang 212013, China.
Cai-Yun LiuSchool of Pharmacy, Jiangsu University, Zhenjiang 212013, China.
Hua-Ping ZhouSchool of Pharmacy, Jiangsu University, Zhenjiang 212013, China.
Chen-Lu XuSchool of Pharmacy, Jiangsu University, Zhenjiang 212013, China.
Ye-Wang ZhangSchool of Pharmacy, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0003-0873-0721
Jiangsu University · CN

Funding

National Natural Science Foundation of China 22068001Natural Science Foundation of Guangxi Province 2021GXNSFAA196005
6 · The paper itself

Abstract

Heparinase I (Hep I), which specifically degrades heparin to oligosaccharide or unsaturated disaccharide, has an important role in the production of low molecular weight heparin (LMWH). However, low productivity and stability of heparinase I hinders its applications. Here, a novel heparinase I (BxHep-I) was cloned from

Indexed as

characterizationexpressionHeparinase Imolecular dockingthermostability

Identifiers

PMID37050390
PMCPMC10097318
OpenAlexW4362582095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.